Systemic lupus erythematosus and malignant histiocytosis.
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Biomedical subjects
Publications and source records attributed to A Jover.
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The authors report a personal experience of 1.159 bronchial fibroscopies performed in 3 years. They review the literature for the indications and results of bronchial fibroscopy (except results on trans-bronchial biopsies). The diagnostic value of this technique is highly superior, where bronchopulmonary cancers are concerned, to the traditional bronchoscopy. Besides these classical indications, the place of bronchial fibroscopy in intensive care, and its help for bacteriological and parasitological diagnoses, must be underlined.
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Out of 440 pleural biopsies done with Abrams or Castelain needle, performed over 11 years in 300 pleural effusions, only 14 incidents of accidents occurred. There were 9 minor ones (intrapleural bleeding, subcutaneous emphysema, pneumoserosa by aspiration). Neoplastic graft along the biopsy tract was observed in 5 cases, of which 4 were primitive malignant mesotheliomas and one a primitive appearing neoplastic pleurisy. The risk of parietal neoplastic seeding runs high in malignant mesothelioma, considering that 11 such cases were included in this series of biopsied patients. This risk is not specific to plaural biopsy and can be encountered in simple thoracentesis. This complication therefore is not a contra-indication to needle biopsy as it is only observed in diseases beyond surgical redemption.
The maximum output of half-expiration (MMFR) or DME 25-75% is studied in 136 subjects, evalued as non obstructive, after the determination of the MEVS/VC X 100. The values noted are reported to the body surface (S) in order to eliminate the biometric differences. A highly close correlation, of the exponential type, is thus put in evidence for each sex between the DME/S and the age of the subjects. The study of the DME in subjects with obstructive Tiffeneau makes possible: a) to determine an inferior limit of the normal condition; b) to bring confirmation of the fiability of the test. The study of the determination of the DME/S is then performed in subjects with normal MEVS/VC X 100 and clinically suspect of bronchial obstruction (tobacco addicts, patients at stage I of chronic bronchitis, asthmatic patients outside the attacks). The DME determination lets appear the presence of a bronchial obstruction in almost one half of the subjects submitted to study.
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