Antibacterial therapy of community-acquired chest infections.
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Anti-Bacterial Agents↗
Biomedical subjects
A Jolley
Publications and source records attributed to A Jolley.
Impairments on neuropsychologic tests of temporohippocampal and frontohippocampal functions and word fluency in remitting schizophrenia and affective disorders.
Experimental neuropsychologic tests were administered to acute patients with schizophrenia and affective psychosis and to normal controls. Patients had remitting illnesses. Tests included memory for recurring digit and block spans (left and right temporohippocampal), digit and block spans (lateralized parietal/frontal), spatial and nonspatial conditional associate learning (frontohippocampal), and oral word fluency to letter-designated categories (frontal) and semantic-designated categories (left-sided). In 81% of schizophrenic patients patterned deficits incompatible with generalized losses of function were disclosed. Patterns were heterogeneous and characterized by (1) the frequency and severity of left temporohippocampal impairment; (2) asymmetric frontohippocampal function such that severity of bilateral impairment was associated with poorer nonspatial learning and superior performance with better nonspatial learning; (3) syndrome relationships predicted by the hemisphere imbalance syndrome model pertaining to positive and negative symptoms and the catatonic syndrome; (4) a generalized deficit independent of temporohippocampal functions; and (5) no relationship between performance and computed tomographic signs or medication. Patients with affective disorders had patterned deficits characterized by bilateral impairments that disclosed a preponderance of deficits in spatial learning and memory; depressives demonstrated impairments in digit span.
Affective Disorders, Psychotic↗
Gestational stress: effects on open-field behaviour and heart rate reactivity in rat offspring.
Home-cage heart rate (HR) and open-field defecation, ambulation, rearing and HR, were recorded in the offspring of mothers who had been exposed to stress during gestation. Compared with controls, experimental animals showed no significant differences in ambulation and rearing, while defecation was significantly lower. The only significant finding on HR was an increase from home-cage level to open-field level in the experimental group. The results confirmed previous findings that illumination level is a useful independent variable in gestational stress studies, and suggested that different types of HR measure yield a similar picture of the HR/defecation relationship, which appears to be a negative function. These conclusions were discussed in the light of other findings in this area, and traditional assumptions about the emotionality construct were questioned.
Animals↗