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Biomedical subjects

A Joós

Publications and source records attributed to A Joós.

15 recordsLinked to original sources
PubMed2001

[Gastrointestinal stromal tumors in our practice].

The classification of tumours originating from the wall of gastrointestinal organs changed dramatically since of electronmicroscopy and immunohystochemistry were introduced. Previously these tumours were classified as leiomyomas, leiomyosarcomas or schwannomas. With the new methods these disorders can be described in more details and unified, and so the change to provide correct prognosis improved. Still, there are some unanswered questions remaining for the pathologists. In our material in the past 5 year we treated 9 patients because of GIST. Most of them were found in the stomach (6), one developed in the oesophagus, one in the small bowel and another one in the rectum. With describe our patients and look at the related articles literature about this important diseases. Though the incidence is under 1% of patients operated on because of gastrointestinal diseases, we would like to share our experiences in treatment.

Adult↗
PubMed2000

[Acute gastrointestinal bleeding caused by a rare, benign tumor of the duodenum (gangliocytic paraganglioma)].

Diagnosis and treatment of massive gastrointestinal bleeding is sometimes very difficult problem in a surgical unit. Authors present a case of a 40 years old female with an atypical source of upper gastrointestinal bleeding. The origin of the bleeding was detected only by intraoperative enteroscopy. The source of the bleeding was a very rare benign tumour of the duodenum (Gangliocytic paraganglioma) which involved the papilla of Vater. During the operation resection of the pedunculated tumour was carried out, with choledochal--and Wirsungoplastyc, associated with external drainage of these ducts. According to the literature in preoperative diagnosis of this rare tumour endoscopy, angiography, and EUS are very useful. In case of malignancy, metastases radical operation-pancreatoduodenectomy--is indicated.

Acute Disease↗
PubMed1995

[Helicobacter pylori in benign gastroduodenal diseases].

(A light- and electronmicroscopic study). We have examined the occurrence of Helicobacter pylori (HP) in 2937 gastric antral biopsy specimens from 979 patients with upper gastrointestinal symptoms. The incidence of HP proved to be 50.5%. The endoscopic diagnoses were: gastritis (62 cases), gastric erosion (425), gastric ulcer (51), duodenitis (22), duodenal erosion (119), duodenal ulcer (122) and the HP incidence was 29, 46, 63,, 50, 66 and 73%, respectively. Microscopic findings were: chronic gastritis (442), chronic active gastritis (356) and normal mucosa (181). The prevalence of HP in these groups was 43%, 78% and 11%, respectively. The activity of gastritis was in good correlation with HP infection. We did not see epithelial damage, and found only a few instances of mucus depletion. Electronmicroscopic examination was performed in order to investigate the morphology of bacterium and its relation to the mucosal cells. We observed mild loss of microvilli on the cell surface and did not see any cell invasion by bacteria.

Adolescent↗
PubMed1993

[Helicobacter detected in children of Helicobacter pylori-positive parents].

The authors examined 48 children of Helicobacter pylori positive parents: 52% were serologically positive for Helicobacter pylori using the Orion Diagnostics Pyloriset Latex agglutination test. Of these children 10 had upper abdominal pain, heartburn and acid eructation and osesophagogastroscopy was performed; seven were found to be Helicobacter pylori positive histologically. These results draw attention to the transmission of Helicobacter pylori infection within families. They suggest that these children should be reviewed regularly, and the diagnostical examinations need to perform if the clinical picture is suspicious of Helicobacter pylori infection.

Adult↗
PubMed1992

[Studying the role of Helicobacter pylori infection in recurrent abdominal pain in children].

The authors studied the role of Helicobacter pylori at recurrent abdominal pain in childhood. Helicobacter pylori infection hasn't been found at the 42 examined children. The endoscopy showed esophagitis in 34 cases. The quick urease test, the histological examination, and the bacterial culture are proposed to carry out in ulcus duodeni, gastritis typ. B ulcus ventriculi and not necessary to carry out if the endoscopy shows only esophagitis--emphasize the authors.

Abdominal Pain↗
PubMed1985

[Endoscopic occlusion treatment in patients with chronic pancreatitis].

Between 1980 and 1983 an endoscopic occlusion of pancreatic duct was performed in 12 patients with chronic pancreatitis. In 4 patients it could be achieved a complete, in 8 patients only a partial occlusion. Four patients became free of pain whereas 5 patients have been operated on following an aggrevation of disease. After one year diabetes mellitus developed in 2 patients. We conclude that the endoscopic occlusion of the pancreatic duct may be recommended in some patients with defined diagnosis and special duct constellation.

Adult↗
PubMed1982

[Angioneurotic edema and hypocomplementemia in patients with thyroid cancer].

The combination with a malignant tumour of angioneurotic oedema (ANO) elicited by a disturbance of the complement system was studied. After surgical removal of the tumour the pathologic complement component level may become normal and the angioneurotic oedema may disappear. In the reported case an angioneurotic oedema, the disturbance of the complement component and scintigraphic deviations of the thyroid suggested the presence of a thyroid carcinoma. After thyroidectomy the ANO disappeared and the complement component returned to normal. This case draws attention to the possibility that, beside lymphoproliferative and autoimmune diseases and cancer of the rectum, carcinoma of the thyroid may also be in the background of angioneurotic oedema.

Adenocarcinoma↗
PubMed1982

Isolated granulomatous disease of the stomach.

A case of isolated granulomatous gastritis observed in a 66-year-old female patient is reported. The gastric granulomatosis gave rise to pyloric stenosis, and at the first explorative laparotomy the change was misdiagnosed for an inoperable tumour. Gastroscopy then revealed the presence of a peptic ulcer, which healed completely on drug therapy. At the second surgical intervention undertaken on account of a relapse after 2 years, Billroth II type resection of the stomach led to complete recovery; the patient has been free from complaints ever since. It is suggested that in addition to peptic ulcer and tumour, isolated gastric granulomatosis should be taken into consideration as the underlying mechanism of pyloric stenosis.

Aged↗
PubMed1980

[Postgastrectomy histological changes, with special reference to cancer].

Postoperative changes of the gastric mucosa were studied in biopsy specimens from patients with resection of the stomach. In 11.4 per cent of cases no changes were revealed. In 70.9 per cent various types of gastritis occurred. After 5 years of partial gastrectomy in 11.9 per cent of cases primary carcinoma of the stump or the anastomosis was found. Considering these data systemic endoscopic control of patients with partial resection of the stomach is recommended.

Autopsy↗
PubMed1979

[Condyloma acuminata].

A review of the clinical features and therapeutic possibilities of condyloma acuminatum is presented on the ground of the ten-year experience of the authors. A giant condyloma simplex with benign clinical behaviour and typical histologic pattern and a case of epithelioma starting from a condyloma simplex and leading to the amputation of the penis are described.

Adult↗
PubMed1978

[Endoscopic stomach polypectomy].

During 33 months in 45 patients 52 times an endoscopic polypectomy was performed in the stomach or in the duodenum. The polyp or the polyposis of the stomach in every case should be clarified with the help of endoscopic polypectomy and histological examination. The histological type of the polyps got in toto determines the therapeutic methods essentially deviating from each other. After a polypectomy a regular gastroscopic control is necessary. The 10% frequency of postoperative bleedings after endoscopic polypectomy may be reduced by improvement of the technique.

Gastroscopy↗
PubMed1977

Lesions caused by copper depletion in the chicken. Light and electron microscopic study.

Lesions of the aorta and other organs of copper depleted layers, roosters, day-old chicks and chick embryos were studied by light- and electron microscopy. Copper deficiency results in late and abnormal development of elastic fibres: inhibition of the formation of cross linkages causes a decline of elastin synthesis. The microfibrils constituting the blackbone of the elastic fibre form a honey-comb pattern. The small amount of amorphous elastin is digestible by elastase, the microfibrils are resistant to the action of the enzyme. The aortic elastic fibres are irregularly shaped, broken revealing a honey-comb like pattern. They maintain an increased affinity to PTA. Tears--dissecting aneurysms--arise in the media, vacuoles appear in the heart muscle, haemorrhages and inflammatory changes may arise in other organs.

Animals↗