Biomedical subjects

A Jenny

Publications and source records attributed to A Jenny.

6 recordsLinked to original sources

PubMed1992

Diagnostic implications of detection of proteinase K-resistant protein in spleen, lymph nodes, and brain of sheep.

Brain, spleen, and selected lymph nodes from sheep with clinical signs of scrapie were analyzed for presence of proteinase K-resistant protein (PrP-res). Diagnosis of scrapie on the basis of detection of PrP-res was compared with diagnosis on the basis of histologic evaluation of the brain from clinically affected or exposed sheep. Proteinase K-resistant protein was found in every brain that was histologically positive for scrapie, and in addition, was found in the brain of several clinically positive sheep that were not diagnosed as scrapie-positive by histologic evaluation. Proteinase K-resistant protein was also found in 87% of the spleens and lymph nodes from sheep that had PrP-res detected in brain homogenates. Therefore, analysis of sheep brain, spleen, or lymph nodes for PrP-res provided a diagnostic approach that was superior to histologic examination alone for detection of naturally scrapie agent-infected sheep.

Animals↗

PubMed1991

The clinical application of neurogenic motor evoked potentials to monitor spinal cord function during surgery.

The purpose of this study was to report results from 300 cases (177 children, 123 adults) administered somatosensory and neurogenic motor evoked potentials during surgery. Of these 300 cases, there were 16 cases of spinal fractures, 16 neurosurgical cases, 28 vascular cases, and 240 cases of elective posterior spinal deformity requiring instrumentation. Results indicated that somatosensory evoked potentials, especially cortical components, demonstrated greater variability than neurogenic motor evoked potentials. Variability was attributed to anesthesia and unknown factors. Neurogenic motor evoked potentials proved to be a more valid indicator of postoperative motor status than somatosensory evoked potentials. Based on their anatomic substrates and results from this study, it was recommended that somatosensory evoked potentials and neurogenic motor evoked potentials be used to monitor spinal cord function during surgery that would place that structure at risk.

Adolescent↗

PubMed1991

Surgical management of sagittal synostosis. A quantitative evaluation of two techniques.

This article reports a retrospective quantitative (cephalic index) evaluation of the effect that two different operations for treatment of scaphocephaly secondary to sagittal synostosis have on cranial shape. Combining our results with those of others, the trend is clear: if the objective of surgical intervention for isolated nonsyndromal sagittal synostosis is normalization of the calcarial width to length ratio, a more extensive procedure than simple or extended craniectomy is required.

Age Factors↗

PubMed1988

Motor organization of the spinal accessory nerve in the monkey.

The segmental and topographical organization of motoneurons of the spinal accessory nerve was studied in monkeys with horseradish peroxidase (HRP). The sternomastoid muscle is innervated primarily from the C1-C2 level of the cord and the motor column is medial in the ventral horn. The trapezius muscle, however, is innervated primarily from the C2-C3-C4 levels of the cord and the motor column lies in the ventrolateral region of the ventral horn. The data are discussed with regard to treatment of torticollis.

Animals↗

PubMed1988

Susceptibility of dogs to infection with Ehrlichia risticii, causative agent of equine monocytic ehrlichiosis (Potomac horse fever).

Adult dogs 1 to 5 were inoculated IV and/or SC with 3, 5, or 6 ml of a suspension containing 1.2 x 10(4) Ehrlichia risticii-infected cells (derived from primary canine monocyte cell cultures)/ml. Dogs 6 to 8 were inoculated IV and/or SC with 3 or 6 ml of 1.2 x 10(5) organism-free cultured canine monocytes/ml. Ehrlichia risticii was isolated in cultures from inoculated dogs 3, 4, and 5 on postinoculation days (PID) 10 to 16, but not from dogs 6 to 8. Dogs inoculated with E risticii seroconverted between PID 6 and 12. Clinical signs of illness were not observed in these 5 E risticii-inoculated dogs. A pony, inoculated with E risticii isolated from inoculated dog 5, developed clinical signs of equine monocytic ehrlichiosis, including fever, anorexia, depression, and diarrhea, and E risticii was isolated from the pony's blood. This E risticii isolate was then inoculated into susceptible dog 9, and E risticii was repeatedly isolated from dog 9 during PID 6 to 17. Dogs were susceptible to infection with E risticii and may serve as a reservoir of the organism in the field.

Animals↗

PubMed1974

[Operation].

Explore the source record for details and available documents.

Humans↗