Epistaxis mortality. The place of blood transfusion in its prevention.
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Biomedical subjects
Publications and source records attributed to A JACOBS.
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Mucosal biopsies from the inside of the cheek show epithelial atrophy, glycogen depletion, and an occasional increase in sulphydryl content in both iron-deficiency and megaloblastic anaemias. These changes are the same in the two types of anaemia but are more marked in the latter group.
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The histological features of the buccal mucosa have been examined in 50 cases of iron-deficiency anaemia, 14 cases of megaloblastic anaemia, and 50 normal subjects. Differences between the anaemic and normal groups have been found and in some anaemic patients striking morphological changes have been seen. These might be due to a direct effect of iron or vitamin B(12) deficiency on the metabolism of the epithelial cells.
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