Biomedical subjects
Publications and source records attributed to A J Lamesch.
Report of a case of massive thymic hyperplasia in a 7-month-old female infant causing a respiratory distress syndrome by displacement and compression of the bronchopulmonary system. Steroid therapy and ventilation were ineffective. Thymectomy had to be performed because of severe respiratory distress. In a review of the literature we did not find any report on a similar case.
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In 200 cases the antireflux plasty by the Cohen advancement technique proved to be a simple and reliable method of reflux treatment. The resulting impossibility of normal endoscopic retrograde catheterization of the ureter after the Cohen procedure. With the patient under general anesthesia the bladder is punctured with a thin trocar by a stab incision at the appropriate pole of the suprapubic skin incision scar. The surgeon directs the trocar under endoscopic control to the ureteral orifice, while an assistant carefully inserts the ureteral catheter into the ureter. This method proved to be easy and without major risk in 5 children.
Bilateral vasovasostomy was performed in 18 dogs and in 60 rats with Ethilon 10-0 and 11-0. The techniques used were: (a) a two-layer technique: the inner muscularis layer and the mucosal layer being sutured separately from the outer muscular layer; (b) a three-point one-layer technique: full-thickness stitches that traverse muscularis and mucosa at 120 degrees, 240 degrees and 360 degrees, between these three-point full-thickness stitches the muscularis layer is closed tightly. Patency of the vasal anastomosis was determined by injection of methylene blue and by vasography. Histologic and electron microscopic studies of specimens were performed at different intervals after the procedure. In a series of 25 rats, the results of the operation were determined by the biological fertility test: there was a 96% pregnancy rate.
Special eyeglasses, designed to be used with the operating microscope, are described. These eyeglasses, which fit inside the eyecups of the oculars of the microscope, give the wearer a better view through the microscope than do conventional glasses and at the same time enable him to shift his vision to the surgical field or the instrument table without a sacrifice in clarity. Because they permit the wearer to maintain the eyecups of the oculars in the "up" position, the eyeglasses also prevent interference from outside illumination.
Vasovasostomy was performed in 20 rats. Vasography then was used to determine the patency of the vas. The scrotum was entered through a longitudinal incision and the scrotal contents were extruded extravaginally. The vas was divided near the epididymis and a 0.4/0.7-mm cannula was inserted into the abdominal end of the vas and contrast medium was injected under fluoroscopic control. The results were documented by radiography. It is concluded that vasography is a reliable method for assessing the success of vasovasostomy in rats.
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In addition to macroscopic studies, microscopic studies, and biologic tests, urography is a valuable method for investigating renal function in rats. Intravenous urography is complicated, however, by the difficulty of puncturing a tail vein or the femoral vein. Intramuscular urography, on the other hand, is a simple and reliable method for radiographic examination of the kidneys and ureters, and gives information on morphology as well as physiology. In this study in 40 rats, intramuscular urography was performed under general anesthesia, and the contrast medium was injected into the gluteal muscles. Dense nephrograms and optimum films of the calices and the ureters were obtained approximately 40 minutes after injection.