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Biomedical subjects

A J Friedhoff

Publications and source records attributed to A J Friedhoff.

At least 127 records · Page 7Linked to original sources
PubMed1975

Phenethylamine in normal urine: failure to verify high values.

The phenethylamine (PEA) level in daytime urine samples of 18 normal subjects was measured by an isotope dilution technique. Purification of PEA from other urinary substance, after the addition of 1-14C-PEA to urine samples, was achieved by the sequence: thin-layer chromatography (TLC), derivatization, TLC, and finally, gas chromatography (electron capture). The estimated mean daily output of PEA was 10.3 mug/day. A circadian rhythm was not evident on the basis of analyses of 24-hr urine collections from four normal subjects. Three acute schizophrenics had levels within the normal means.

Carbon Radioisotopes↗
PubMed1974

Follow-up of children overexposed to lead.

The purpose of this study is to assess the nature and magnitude of the deleterious health effects of subclinical over-exposure to lead in children. The study stems from concerns about the impact on the health of children in city slums who ingest leaded paint without overt evidence of poisoning and the health implication of rising levels of lead in the environment from automotive emissions. The study sample was derived mainly from a registry of children on whom blood lead determinations had been made by the New York City Department of Health and was supplemented by siblings of the registry cases and children from a lead belt area who had extractions of deciduous teeth in dental clinics. Information was obtained through parental interview, medical records, and psychometric evaluation. The data show that deleterious health effects occur in children who were treated for severe lead poisoning and in children without diagnosed lead poisoning who had elevated blood leads (>/=0.06 mg-%). In the absence of diagnosed lead poisoning or elevated blood leads, excess lead exposure, measured in terms of high levels of lead in teeth, was not associated with deleterious health effects.

Adolescent↗