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Biomedical subjects

A J Derbyshire

Publications and source records attributed to A J Derbyshire.

16 recordsLinked to original sources

Observer bias as a factor in neonatal hearing screening.

To evaluate observer bias as a possible factor influencing neonatal hearing testing, two trained observers were asked to evaluate the behavior of 200 neonates at a moment the observers thought a stimulus was being presented. Observers were receiving masking noise, and when the stimulus button was pressed a stimulus might or might not be delivered to the child. Results suggest that observer bias is not a factor when arousal is the only acceptable response and is clearly defined, and the observers are limited to a yes-no decision. Sequential analysis of infant response patterns is presented and a specific test scoring protocol is outlined.

Arousal↗

Averaged evoked potentials in cats with lesions of auditory pathway.

Averaged evoked activity was recorded from needle electrodes placed at the vertex of the calvaria and adjacent to each bulla in anesthetized cats in response to click stimuli. The portion of the response from 0 to 10 msec was analyzed. Activity during the first 3 msec was greatly reduced on the side ipsilateral to a lesion involving destruction of the cochlea or section of the eighth nerve and its blood vessels. Activity after 4 msec was greatly reduced on the side ipsilateral to destruction of the cochlear nuclei. No effect was found with destruction of both inferior colliculi. The bulla-vertex evoked responses were also compared to those recorded from the round window. The results support the premise that change in the wave-form of the early evoked potential can be used to determine site of loss of acoustic information along the auditory pathway.

Acoustic Stimulation↗

Lost potentials.

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Analysis of Variance↗