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Biomedical subjects

A Iwabuchi

Publications and source records attributed to A Iwabuchi.

46 records · Page 3Linked to original sources

The treatment of pyogenic bone and joint infections by closed irrigation-suction.

An improved method of closed irrigation-suction treatment of bone and joint infections is described. The method utilizes a crisscross flow-reversal system using a double tube which prevents obstruction of the tube. A series of 154 patients with acute and chronic bone and joint infections were treated with closed irrigation in 172 closed irrigation-suction procedures. One hundred forty-eight cases (86.0%) were treated successfully, 7 cases (4.1%) were improved, and 17 cases (9.9%) were failures. Blood concentration levels of antibiotics were examined during closed irrigation. Absorption of antibiotics from the wound was insignificant. Culture and sentivity tests of drainage during closed irrigation are used to monitor the cleansing of the wound. Serum hepatitis was seen in 4 cases within the hematogenous group and in 6 cases within the traumatic group. Postoperative bleeding during irrigation was an important complication.

Adolescent↗

Rupture of the pectoralis major. Report of 2 cases.

Two cases of rupture of the pectoralis major are reported, one caused by excessive tension and direct violence, while the other was a result of direct violence alone. The site of the rupture was at the lateral third portion of the pectoralis major in one and at the musculotendinous junction in the other. Both patients were treated surgically, and regained full function of their shoulders. Review of the literature suggests that surgical repair is generally advisable and more gratifying than conservative management.

Adult↗

Presence of Philadelphia (Ph) chromosome-negative cells in Ph-positive chronic myelogenous leukemia.

Six cases of chronic myelogenous leukemia (CML) with coexistence of cells with a Philadelphia (Ph) translocation and a normal karyotype are described. Molecular analyses were performed in 3 of the 6 cases at two phases with different cytogenetic findings. Among the 6 cases, 4 cases were late appearance of a Ph chromosome. Two of the 3 patients analyzed had major breakpoint cluster region (Mbcr) rearrangements; aberrant Mbcr fragments were observed whether the cells had a Ph translocation or not. The remaining one did not show any rearrangements within the Mbcr DNA sequences.

Adult↗