The immunoprophylaxis and immunotherapy of Pseudomonas infections in burns with polyvalent Pseudomonas aeruginosa corpuscular vaccine.
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Biomedical subjects
Publications and source records attributed to A Ionescu.
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In connection with a clinical observation the authors refer on this rare complication of duodenal ulcer situated above the Vater ampula. Fistulization in the transverse colon led to a short-circulting of the small bowel and an advanced cachectic condition. Surgery consisted in the suppression of the fistula that had developed between the duodenum and the colon, associated with anterior duodeno-papillo-antrectomy, Judo piloroplastia and bilateral, sub-diaphragmatic troncular vagotomy, and resulted in the recovery of the patient.
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From the leaves and seeds of some Plantago species (Plantago major, media, lanceolata) the polyholozidic fraction was separated. A statistically significant gastroprotective action was found both in the case of the polyholozide obtained from seeds and leaves in two experimental models. At higher doses a laxative action was also obtained.
The localization of hexacanth embryo at spleen level is quite rare, although, in frequency order, it is the third affected organ after liver and lung. The infestation of the spleen usually takes place by arterial route after the parasite has passed through the two other filters, hepatic and pulmonary. The retrograde venous route, which avoids the liver and lung, is also considered. The diagnosis of splenic echinococcosis is made with the clinical, epidemiological and laboratory findings. The treatment is surgical, consisting, most commonly, in splenectomy; the anastomoses of splenic hydatid cysts with the digestive tube are indicated only in those cases with peculiar evolutive forms; cystotomy, with removal of the content and drainage of the remnant cavity, surgery performed either on abdominal or lumbar route, is the method of choice in the suppurated cysts which fix, by adherences, the spleen to its lodge.
An observation is presented, of a female patient aged 62 years with a large abdominal tumour. Clinical and para-clinical examinations could not establish the organic origin of the formation. Surgery disclosed a giant tumour developed in a gastric diverticulum situated under the cardia. The patient had suffered for a long time with gastric symptoms and her antecedents included upper digestive haemorrhage which was attributed to gastric ulcer according to radiological examination. In retrospect it was established that the disturbances were determined by a gastric diverticulum, complicated by haemorrhage and which later on had become malignant. In spite of its extraordinarily large size the tumour was removed by total gastric resection, in an attempt to treat radically the cancer.
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The rheumatoid factors constitute one of the major autoantibodies in rheumatoid arthritis (RA). In this study, for the quantitative determination of the RF IgM class, in serum and synovial liquid of patients with RA and JRA, we used the hemagglutination principle and both liquid and lyophilized reagents. The results we obtained demonstrated the superiority regarding the stability, the reproducibility and the possibility of micromethod standardization with lyophilized reagent.
Based on two cases of nonsecreting malignant adrenal tumors the authors make some clinical and therapeutical considerations. These tumors are rare, have a longer evolution without significant clinical manifestations, may reach considerable size and may become complicated, most frequently by intratumoral hemorrhages and necroses, which usually favour an infection, and more rarely by their rupture. The diagnosis is based on the clinical and laboratory findings. The treatment is surgical, associated with chemotherapy and radiotherapy. The survival interval is long, sometimes exceeding 10 years.
The authors present a statistics on 32 cases of proctosigmoid junction cancer and discuss diagnostic and management aspects. This localization of the colorectal cancer has certain characteristic features, among which most important are its severe complications. The treatment of choice is the high anterior proctosigmoid resection with restoration of digestive passage, with or without colostomy. In the complicated cases the interventions will be performed in two or even three stages. Hartman's surgery is also indicated in the complicated cancers and in the compromised patients. The postoperative mortality remains high.
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