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Biomedical subjects

A Incze

Publications and source records attributed to A Incze.

29 records · Page 2Linked to original sources
PubMedDate not supplied

Antiarrhythmic effects of verapamil given in sublingual way.

In order to eliminate the first pass through the liver where the drug is deactivated, 80 mgs verapamil was given in sublingual way in a) 10 patients with supraventricular tachycardias where in 7 instances sinus rhythm was obtained after 15-30 minutes, b) in 18 patients with atrial fibrillation and in 5 with atrial flutter with rapid ventricular rate, where a significant slowing down of ventricular rate was obtained after 20 minutes. The sublingual way of verapamil administration is a simple, effective and safe procedure in the treatment of tachyarrhythmias.

Administration, Sublingual↗
PubMedDate not supplied

Experimental validation of sino-atrial conduction time using sinus node potential recording, right and left atrial continuous pacing method.

In an experimental study indirect sino-atrial conduction time (SACT) was measured, using continuous pacing method from right and left atrial sites, and compared with direct SACT obtained from sinus node potential recording, all the determination being done before and after autonomic blockade. The distance between the two sites of stimulation may be taken into account as a correction factor for SACT determination. The SACT obtained with sinus node potential technique is the same as the indirect SACT after autonomic blockade. These findings are valuable for SACT determination with transesophageal pacing method. Left atrial pacing, thus transesophageal pacing, is a valuable method in estimating the SACT, but a time correction and autonomic blockade is required in order to obtain a real value, eliminating the extrinsic influences.

Animals↗
PubMedDate not supplied

Transesophageal pacing technique in the estimation of sinus node function.

A personal noninvasive transesophageal pacing technique for the estimation of sinus node function is presented. With a pacemaker device and an esophageal pentapolar catheter, using a correction factor for the left atrial site of stimulation, it is possible to calculate the sinus node recovery time, sinoatrial conduction time and sinus node effective refractory period, before and after autonomic blockade as accurately as by the intracavitary technique.

Autonomic Nerve Block↗
PubMedDate not supplied

Computerized system for assessing heart rate variability.

The principal theoretical, methodological and clinical aspects of heart rate variability (HRV) analysis are reviewed. This method has been developed over the last 10 years as a useful noninvasive method of measuring the activity of the autonomic nervous system. The main components and the functioning of the computerized rhythm-analyzer system developed by our team are presented. The system is able to perform short-term (maximum 20 minutes) time domain HRV analysis and statistical analysis of the ventricular rate in any rhythm, particularly in atrial fibrillation. The performances of our system are demonstrated by using the graphics (RR histograms, delta RR histograms, RR scattergrams) and the statistical parameters resulted from the processing of three ECG recordings. These recordings are obtained from a normal subject, from a patient with advanced heart failure, and from a patient with atrial fibrillation.

Algorithms↗