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Biomedical subjects

A Igata

Publications and source records attributed to A Igata.

191 records · Page 11Linked to original sources
PubMedDate not supplied

Morphometric analysis of intramuscular nerves.

Intramuscular nerves were obtained at autopsy from five adult controls and were morphometrically analyzed. The number of myelinated fibers was directly proportional to the diameter of the fascicles. The fascicles were grouped into six sizes according to diameter. For each group, the normal range of distribution of the number of myelinated fibers could be estimated. Fiber size distribution and myelinated fiber density were also calculated. A unimodal fiber size distribution was observed for the small fascicles (less than 50 microns in diameter), and a bimodal pattern was observed for the large fascicles. Total myelinated fiber density was high in the small fascicles, and it decreased as the fascicles became larger in size, approaching the values observed in the large peripheral nerves. This study will be helpful in objectively evaluating morphological changes of intramuscular nerves in adult neuromuscular disorders.

Adult↗
PubMedDate not supplied

Toward a society of maturity and harmony - a new plan for achieving longer and healthier life expectancies in Japan.

Because of its rapidly increasing older population, Japan urgently needs sound and rapid progress in gerontology in order to create a new society, in which both young and old can live their active and creative lives in harmony. In order to establish such a society of maturity and harmony, the Japanese Government has begun a major national project, heralded by the establishment of a National Research Center of Gerontology. This center will begin functioning in 1995 in Nagoya, with the combined support of the National and the Aichi Prefectural Governments. This center will consist of a newly constructed research institute of 8000 m(2) with an attached animal facility, and a geriatric hospital with 500 beds for patients with dementia, those in a bed-ridden state, as well as those with various geriatric diseases. The close collaboration of the hospital and the research institute is expected to facilitate further progress in gerontology as well as in the education and training of specialized geriatricians and future leaders in gerontological research in Japan. In order to promote rapid progress in gerontology, a new foundation, the Japan Foundation for Aging and Health, has already begun its activities including the financial support of gerontological research, an international exchange program for scientists in gerontology, and the holding of international symposia in various fields of gerontology. With this accomplishment of the new Institute in 1995, activities for international collaborations will be dramatically expanded. This paper briefly covers the history as well as some future prospects of gerontology in Japan in conjugation with the establishment of the National Research Center of Gerontology.

Journal Article↗
PubMedDate not supplied

[Awareness and feelings of elderly patients and their families concerning disease during terminal hospitalization--malignancy versus non-malignancy].

We conducted a questionnaire survey on the awareness and feelings of elderly patients and their families concerning their diseases and prognosis during terminal hospitalization. Sixty-five families of 177 patients who died at our hospital in 1992 answered questions concerning estimation of the prognosis, understanding of the disease, satisfaction regarding explanation of the disease, wish to be informed of the diagnosis, feelings during hospitalization, and whether the family revealed the diagnosis to the patient. Patients with malignancy were not informed of the true diagnosis at this time. As to estimation of the prognosis, patients aged 70 or older who did not expect "cure" of their diseases at first were significantly fewer, and those anticipating "death" just before dying were significantly more frequent than those under age 70. In patients with malignancy, those aged 70 or older foresaw "incurability" at first significantly more frequently than those under age 70. Patients with malignancy knew the diagnosis in significantly fewer cases, believed the false diagnosis significantly more frequently, and showed dissatisfaction with the explanation of the disease significantly more frequently, than those with non-malignancy. Proportions of the family who told the diagnosis to the patient were 11.8% in malignancy and 38.8% in non-malignancy with statistical significance. These data indicate that medical care during terminal hospitalization should be modified principally based on informed consent, if that is the wish of the patient.

Aged↗