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Biomedical subjects

A Iannaccone

Publications and source records attributed to A Iannaccone.

At least 55 records · Page 3Linked to original sources
PubMed1978

Urinary kallikrein activity of workers exposed to lead.

Two groups of men of different age ranges and with the same period of lead exposure were selected for study in a recently opened car-battery factory. Two other groups of age-matched men, not exposed to heavy metals in their work, were used as controls. Morning urines were collected from control and exposed groups for determination of urinary kallikrein activity, urinary delta-amino-levulinic acid (ALA) and lead levels. The environmental lead levels and the urinary ALA and lead values indicated that exposure in the factory was not heavy. The older group of lead-exposed workers showed greatly reduced urinary kallikrein activity compared with that of the age-matched controls. In contrast, the younger group did not show any significant alteration in urinary kallikrein excretion.

Adult↗
PubMed1978

Glucose-6-phosphate dehydrogenase in kidneys of lead-poisoned rats and adrenalectomized rats.

Glucose-6-phosphate dehydrogenase (G6PDH) activity, assayed biochemically, was significantly increased in kidney homogenates of lead-poisoned rats when compared with controls. Histochemically, G6PDH activity was greatly increased both in the distal tubules and the macula densa, but showed no significant changes in the proximal tubules. Biochemical assay of G6PDH in kidney homogenates of adrenalectomized rats was three times that in control animals. In this condition also, histochemical staining showed G6PDH activity to be increased in both macula densa and distal tubules. This demonstrates an increase in G6PHD in two completely different experimental conditions and suggests that the distal renal tubule in the rat might operate in functional unity with the macula densa.

Adrenalectomy↗
PubMed1978

[Quantitative analysis of low concentrations of cristobalite in thin layers by x-ray diffraction].

A new x-ray diffraction procedure for the determination of cristobalite in the presence of amorphous silica is described. The standards are obtained by deposition of thin layers of watery suspensions of cristobalite and amorphous silica mixtures on silver or lead disks or cellulosa filters. Six calibration curves are then calculated to reduce weight and sampling errors. Six mcg of cristobalite mixed with 594 mcg of amorphus silica is the lowest detectable limit. The method may be used for the analysis of both raw materials and respirable dust.

Air Pollutants↗
PubMed1978

[Urinary kallikrein in cadmium-exposed workers].

The urinary kallikrein activity was determined in a group of 20 young workers exposed to cadmium and to lower concentrations of lead and other toxic agents. Two of them were suffering from labile hypertension. The urinary kallikrein activity of exposed workers was found to be reduced by more than 80% in comparison with a control group.

Adult↗
PubMed1977

[Identification, using x-diffractometry, of chromium, lead and zinc compounds in pigments of protective paints].

The application of diffractometric techniques for the identification of crystalline compounds which are contained in paint pigments and are important from the hygienic point of view, is described. Particularly, it is possible to identify lead and zinc chromates either on untreated pigments, or on filters of air samples of work-places used for spray painting.

Air Pollutants, Occupational↗
PubMed1977

[Atmospheric concentration of mercury in chlorinated sodium carbonate plants and their vicinity].

The mercury control in the chloroalkali plants is a "routine method". The air is above all sampled in the chloroalkali electrolysis rooms and in the rooms under them. Already in a previous paper we had pointed out a method for the sampling and determination of the metallic mercury in these work rooms. Atmospheric samples are passed through a small glass tube containing fine spongy particles of metallic gold. As far as particle mercury sampling and analysis are concerned, environmental air is filtered by micropore filters placed on the top of the small tube filled with the gold sponge (on the same sampling line). The present work has been made with the purpose of verifying the percentage of metallic and particle mercury of the chloroalkali plants and nearby the industrial perimeter of these plants. The results have been obtained from data of two plants with different capacity, different topographic location and different microclimatic conditions. It has been noticed that the air concentration of mercury in the surrounds of the plants is higher than the basal values in incontaminated areas and the ratio between metallic mercury and particle mercury in the surroundings of chloroalkali plants is casual. The obtained data have been explained at the light of the microclimatic observations and exactly: speed and direction of winds, temperature, humidity and rainy precipitations.

Air Pollutants↗
PubMed1977

[Urinary kallikrein and risk of lead poisoning].

Urinary kallikrein is an enzyme, probably originated in the kidney, which acts on plasma kininogen to produce kallidin, the decapeptide precursor of bradykinin, and appears to be implicated in various forms of arterial hypertension. It is significantly decreased in workers exposed to lead showing no hypertension or other clinical signs of lead poisoning. In respect to measurement of ALA or other heme precursors the determination of urinary kallikrein seems to be able to detect a different, and perhaps in certain cases earlier, effect of lead intoxication on enzyme functions.

Adult↗