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Biomedical subjects

A I Tsyganov

Publications and source records attributed to A I Tsyganov.

At least 19 recordsLinked to original sources

[Multifield local hyperthermia as a method for heating deeply located neck tissues].

Distribution of the thermal field in neck tissues in local SHF-hyperthermia is studied. The two-field method of irradiation permits a uniform heating of more deeply located layers of the tissue due to summation of the radiant energy. So, the contact method of irradiation using "Luch-2" and "Luch-3" sets permits elevating the temperature inside the larynx up to 41-41.5 degrees C and maintaining it under given conditions for 25-30 min, but the heat loading on the skin and subcutaneous fat remains high. When using noncontact irradiators and "Parus" set the deeply located neck tissues are heated to 42-43 degrees C, the temperature of surface layers not exceeding 41-42 degrees C. This temperature rate is possible to be maintained for 25 min; its prolongation induces a sharp rise in the temperature of surface layers. Long-term SHF-hyperthermia of deeply located neck tumours necessitates cooling of the integument surface.

Animals↗

[Radiation therapy with local UHF hyperthermia in the late stages of laryngeal cancer].

Altogether 47 patients with advanced laryngeal and laryngopharyngeal tumors were treated. Twenty-six patients received multimodality therapy including local UHF-hyperthermia and gamma-beam therapy; 21 patients receiving radiotherapy only were entered in the control group. Hyperthermia was induced by the electromagnetic field with the frequency of 2450 and 915 MHz. Parus and Plot units were used. External irradiation was provided. Clinically, complete primary tumor regression was achieved in 20 of 26 patients. A positive effect was absent in 3 cases when metastasis size was 10 X 12 X 8 cm. In the control group, clinically complete tumor regression was noted in 2 patients only. In 4 cases the effect was insignificant, in the rest of 15 cases various degrees of a decrease in tumor and metastasis sizes were revealed.

Combined Modality Therapy↗