[Fluorimetric determination of substances on chromatograms and electrophoregrams].
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Chromatography, Paper↗
Biomedical subjects
A I Medvedev
Publications and source records attributed to A I Medvedev.
[Effect of gamma-irradiation of various plant seeds on the metabolism of tyrosine, phenylalanine and 3,4-dioxyphenylalanine in plant shoots].
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Gossypium↗
[Effect of ionizing radiation on the metabolism of tyrosine and phenylalanine in irradiated plants].
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Phenylalanine↗
[2 routes to lysine biosynthesis in higher plants].
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Adipates↗
[Densitometric determination of nucleic acids in gels after electrophoresis].
A technique for the quantitative determining of nucleic acids after electrophoresis by double-wave densitometry in UV spectrum by scanning agar gel along both axes was developed. Optical characteristics of agar and acrylamide-agar gels are given. The range of quantities measured is 6 divided by 30 micrograms of DNA per gel; the standard deviation adjusted to 1 microgram is less than +/- 3%.
Animals↗
[Interaction of a natural modifier of lethal effect of radiation with HeLa cells].
Polypeptide 14C-aspartyl glutamate, a chemical analogue of a natural modified of a lethal effect of radiation, has been synthesized. The modifier was shown to react readily with nucleic acids and proteins of non-irradiated cells: the reaction was considerably enhanced when the modifier was administered simultaneously with radiation of cells. As is known from the literature, a molar concentration of the incorporated polypeptide is considerably lower than the intracellular molar concentration of an active radiosensitizer, BUdr, which produces an effect on mammalian cells comparable with that of polypeptide.
Culture Media↗
[Strongly acid polypeptides as inhibitors of the repair of single-stranded DNA breaks induced by gamma irradiation].
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DNA Repair↗
[Effect of low molecular weight polyacrylic acid on normal and gamma-irradiated Chinese hamster cells].
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Acrylic Resins↗
[Effect of natural and synthetic acid polypeptides on normal and gamma-irradiated cells of the Chinese hamster].
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Animals↗
[Study of combined chronic effects of gamma radiation and lead on the occurrence and repair of DNA injury in mice].
It has been shown that neither exposure of mice to lead in the drinking water (20 mg/l) for 50 days nor chronic gamma-irradiation of animals (1.5 Gy, 1.3 mGy/h, 50 days) induces single-stranded DNA breaks in thymocytes. Acute gamma-irradiation (1 and 4 Gy) of lead-pretreated mice resulted in an inhibiting of repair of radiation-degraded DNA in thymocytes and in an increasing of the level of DNA lesions detected in erythroblasts of bone marrow by the micronuclear test method. Inhibition of ssDNA break repair in thymocytes caused by lead was not seen upon exposure of mice to combined chronic action of gamma-irradiation and lead. Chronic irradiation did not affect the micronuclei rate increase revealing after acute irradiation of lead-treated mice.
Age Factors↗