Search PubMed⌕ Search

Biomedical subjects

A I Macpherson

Publications and source records attributed to A I Macpherson.

At least 37 records · Page 2Linked to original sources
PubMed1976

Peripheral aneurysms in Behĉet's disease.

Two patients with Behĉet's disease are reported, both of whom had aneurysms of peripheral arteries. In one the aneurysms were multiple. The aneurysm was replaced with a Terylene prosthesis in one patient, and in the other an autogenous vein bypass was used. In each case a further aneurysm developed adjacent to the vascular anastomosis. Severe ischaemia of the affected limbs subsequently developed in both patients.

Adult↗
PubMed1976

Assessment of portasystemic shunt patency by estimation of D-xylose excretion.

The D-xylose excretion test appears to be a useful method of monitoring shunt patency after a portasystemic venous anastomsis for portal hypertension. A 5-hour urinary excretion greater than 6 g appears an acceptable indicator that the shunt is patent. A second criterion of patency is an increase of 4 g or more over the result of preoperative tests. If the excretion rate falls in the postoperative period or remains less than 4-2 g/5 h, the anastomosis may be assumed to be occluded.

Adolescent↗
PubMed1975

Planned splenectomy in treatment of idiopathic thrombocytopenic purpura.

The results of a policy of treatment in idiopathic thrombocytopenic purpura based on previous observations on the natural history of the disease and its response to corticosteroids are described. The results of splenectomy were better when the history was less than 100 days. Three patterns of response to splenectomy were observed: complete remission, symptomatic remission, and relapse. The prognosis can be determined by the level of the platelet count six weeks after splenectomy. Corticosteroid treatment for more than three weeks before splenectomy noticeably increased the incidence of complications after operation. Splenectomy can safely be performed in pregnancy. The decision to operate should be made on the maternal condition and its response to corticosteroids.

Adolescent↗
PubMed1975

The relationship between ultrasound assessment and angiography in occlusive arterial disease of the lower limb.

The Doppler ultrasound technique has been used to assess the haemodynamics of the peripheral circulation in patients with arterial disease. Using this method the resting pressure index and the response after exercise of the systolic pressure at the ankle was determined in 62 limbs. Following exercise, four patterns of abnormal response to exercise were found and graded in severity from 1 to 4. A single aorto-iliac lesion was associated with a normal or slightly reduced resting pressure index but with a severe reduction of pressure (grade 3-4) after exercise. A single femoropopliteal lesion was usually associated with a low resting pressure index but only a slight (grade 1-2) fall after exercise. A low resting pressure index and a severe postexercise grade were found in patients with multiple occlusions. Disease of the profunda femoris artery was associated usually with both a low resting pressure index and a grade 3-4 post-exercise curve.

Adult↗
PubMed1971

Unusual particles in splenic disorders.

Virus-like particles have been seen on electronmicroscopic examination of four spleens surgically removed for haematological disorders-three cases of idiopathic thrombocytopenic purpura and one case of haemolytic anaemia. The particles were approximately spherical and 50-60 nanometres in diameter.

Adult↗