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Biomedical subjects

A I Larsen

Publications and source records attributed to A I Larsen.

32 records · Page 2Linked to original sources
PubMed1991

Gender-specific reproductive outcome and exposure to high-frequency electromagnetic radiation among physiotherapists.

The aim of this case-referent study was to investigate reproductive hazards other than congenital malformations after exposure to high-frequency electromagnetic radiation. Cases and referents were sampled from a cohort of pregnancies of members of the Union of Danish Physiotherapists through linkage of the union file with national medical registers. Case groups were spontaneous abortions and children with low birth-weight prematurity, and stillbirth/death within one year. Exposure to high-frequency electromagnetic radiation before and during pregnancy was assessed through telephone interviews. As referents to the 270 cases, 316 pregnancies were randomly sampled. A total of 8.4% did not participate. Only 23.5% of the children born by the highly exposed mothers were boys. This value is a statistically significantly altered gender ratio showing a dose-response pattern. High-frequency electromagnetic radiation was furthermore associated with low birthweight, but only for male newborns. The other outcomes were not statistically significantly associated with exposure to high-frequency electromagnetic radiation.

Adult↗
PubMed1991

Congenital malformations and exposure to high-frequency electromagnetic radiation among Danish physiotherapists.

A cluster initiated the present case-referent study to assess the relation between exposure to high-frequency electromagnetic radiation and congenital malformations. Through the linkage of a cohort formed from a union file of Danish physiotherapists with complete national registers of pregnancy outcome, cases (pregnancies terminated by the birth of a malformed child) and referents were identified. From responses in a blinded telephone interview without knowledge of case status, exposure to high-frequency electromagnetic radiation in the first month of pregnancy was assessed. Indices reflecting duration of exposure ("time") and maximum level of exposure ("peak") were composed. After a 7% dropout 54 cases and 247 referents were interviewed. No statistically significant associations between pregnancy outcome and high-frequency electromagnetic radiation were found (odds ratio 1.7, 95% confidence interval 0.6-4.3).

Abnormalities, Radiation-Induced↗
PubMed1990

[Assessment of exposure to organic solvents. Reading the label or the legally compulsory instructions for use are not enough].

A case history is quoted to illustrate the description of exposure to organic solvents and to illustrate the following points: 1) It is not possible to assess the degree of exposure qualitatively by registering of legally correctly written labels and instructions for use. 2) Quantitatively correct prescriptions of the products do not reflect the quantitative conditions of exposure and 3) Thermodynamic calculations which also consider how the individual components influence the rates of vaporization of one another can describe the conditions of exposure more precisely.

Brain↗
PubMed1990

Contact allergy to the fungicide benomyl?

Benomyl is a widely used fungicide. Contact allergy to benomyl has been reported in a few cases. We describe a group of 62 workers, exposed to benomyl. None had contact dermatitis from benomyl. It appears that benomyl at most is a weak sensitizer. We suggest that earlier-reported allergy may represent cross-reactions and/or that the development of contact allergy to benomyl requires previous exposure to other chemically related pesticides.

Adult↗
PubMed1987

Low-dose heparin in the treatment of calcaneal peritendinitis.

A double-blind, controlled study is presented on the effect of low-dosage heparin on acute calcaneal peritendinitis crepitans in young men. Treatment consisted in exemption from physical work and subcutaneous injection of heparin. 5000 I.U., or placebo, once a day for 5 consecutive weekdays. During the first week the mean total symptom score showed a gradual fall to 32 and 34% of the baseline values in the heparin (n = 10) and the placebo group (n = 10), respectively. On day 15 the value was unchanged in the heparin group, whereas it had increased again to 45% in the placebo group. However, the symptoms and signs recorded never differed significantly between the two groups. No adverse reactions were observed. Consequently, further studies are needed to show whether a treatment of acute peritendinitis can be obtained with heparin in a dosage with less risk of bleeding than that involved in the previously reported regimen.

Achilles Tendon↗
PubMed1987

Pain relief after major abdominal surgery: a double-blind controlled comparison of sublingual buprenorphine, intramuscular buprenorphine, and intramuscular meperidine.

In a double-blind randomized study of three groups of 18 patients scheduled for major abdominal surgery the efficacy and side effects of sublingual buprenorphine were tested and compared to intramuscular meperidine and buprenorphine. Single doses of either 75 mg of meperidine, 0.4 mg of sublingual buprenorphine, or 0.3 mg of intramuscular buprenorphine were used. Patients given buprenorphine as sublingual tablets were significantly more conscious in the immediate postoperative period (Glasgow Coma Scale) than when given buprenorphine or meperidine intramuscularly. Median pain intensity differences (PID) showed equal pain relief, whereas the summarized pain intensity differences (SPID) were significantly higher in the intramuscular buprenorphine group compared to the meperidine group. Three cases of respiratory acidosis in the meperidine group required IPPV treatment, and one case in the intramuscular buprenorphine group required treatment. Sedation and nausea were the most common side effects in all three groups. We conclude that sublingual buprenorphine is useful for relief of postoperative pain and exhibited administrative advantages, when the patients were able to cooperate.

Abdomen↗