Biomedical subjects
Publications and source records attributed to A I Iagniuk.
The results of surgical treatment of 339 patients with an acute ileus (AI) were analyzed. Severe disorders of water-electrolytic, protein metabolism and immune status in 62 patients were revealed. Method of treatment of functional postoperative AI with application of serotonin adipinate was proposed.
In experiment on white rats in was established that after the truncal vagotomy performance in the stress gastric ulcer the lowering of the serotonin and histamine blood content was noted as well as the disorder of ratio of their concentration in gastric wall. Insufficiency of serotonin causes the disorder of gastric motor-evacuation function after the operation. Administration in postoperative period of serotonin adipinate had promoted the raising of serotonin concentration in blood and gastric tissues, histamine level lowering, enhancement of serotonin/histamine ratio.