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Biomedical subjects

A I Eidelman

Publications and source records attributed to A I Eidelman.

At least 19 recordsLinked to original sources
PubMed1990

Epidemiology of group B streptococci colonization and disease in mothers and infants: update of ongoing 10-year Jerusalem study.

A study in 1984 of the colonization rates of Group B beta hemolytic streptococci (GBS) in 257 Jewish and 189 Arab parturient women revealed rates of 5.4 and 1.6% respectively. In 1987, a study of 116 Jewish women noted a rte of 3.5%. GBS colonization rates in the newborns of the three groups were 1.8, 1.3 and 1.1% respectively. No statistically significant differences were noted between any of the maternal or neonatal groups. A review of the period 1982-87 revealed a GBS neonatal sepsis attack rate of 0.2/1,000 live births. These data confirm the persistent low incidence of GBS colonization and disease in the Jerusalem area.

Carrier State↗
PubMed1989

Screening for hypoglycemia with plasma in neonatal blood of high hematocrit value.

A model utilizing human umbilical cord blood was used to screen for hypoglycemia in a simulated neonatal situation. The aims of the study were to assess the effect of increasing Hct concentration on Dextrostix readings, and to determine whether plasma samples, in contrast to conventional whole blood samples, were acceptable for Dextrostix determinations in selected cases. Dextrostix readings were determined on 65 whole blood samples of varying Hct, and on plasma specimens, 48 of which were paired with whole blood samples. The results were compared with plasma true glucose values. Plasma Dextrostix readings correlated well with true glucose values throughout the entire Hct range (r = .94, slope = 1.16). Whole blood Dextrostix readings, on the other hand, were Hct-dependent and, with increasing Hct values, became falsely low. As a result, a Hct values greater than 70%, whole blood Dextrostix readings were less than 50% of the true glucose value (r = .94, slope = 0.45). Plasma Dextrostix determinations may offer an accurate means of screening for neonatal hypoglycemia in asymptomatic infants with high Hct, pending laboratory glucose results.

Blood Glucose↗
PubMed1989

Phototherapy--1988. A green light for a new approach?

Neonatal hyperbilirubinemia or, as otherwise known, jaundice of the newborn is the most common clinical problem in the newborn period. Visible jaundice is seen in 30% to 50% of infants, and in about 10%, the hyperbilirubinemia requires treatment. The critical factor that leads to the accumulation of this yellow pigment bilirubin is the immaturity of the newborn's liver and its inability to excrete the natural form of unconjugated bilirubin. In the past two decades phototherapy has become the routine both for treatment of neonates with hyperbilirubinemia and for prophylaxis in highrisk patients such as preterm infants. Recent information about the mechanism of phototherapy and the availability of new types of light sources prompted this review.

Color↗
PubMed1988

The grandmultipara: is she still a risk?

Grandmultiparity is reported to increase both maternal and perinatal mortality and morbidity. Unique religious and demographic factors in Jerusalem allowed us to analyze a population wherein parity could be dissociated from socioeconomic status. A total of 7785 mothers was studied, 889 (11.5%) of whom were grandmultiparas. Comparison of grandmultiparous mothers with all others revealed no increase in the incidence of hypertension, diabetes, uterine atonia, antenatal or postnatal hemorrhage, cesarean sections, stillbirth rate, or congenital malformations. The grandmultipara had significantly lower neonatal mortality and low birth weight rates and a significantly higher incidence of multiple births and trisomy 21 (p less than 0.01). These results strongly suggest that grandmultiparity in and of itself in a healthy, economically stable population afforded modern medical care is not a major risk factor and that previous reports primarily reflected social class factors and not parity per se.

Female↗
PubMed1988

Infants' face-recognition by primiparous and multiparous women.

We have compared the ability of 49 primiparous and 75 multiparous women to recognize photographs of their newborn infants. In line with previous research on infant cries, we found that multiparous women who had been with their infant 0.5 to 5.0 hr. were significantly more successful in recognizing their infants' photographs than primiparous women with comparable exposure to their newborns. For women who had not been with their infants more than 5 hr., parity was not related to recognition. We propose that the transient performance deficit of the primiparous women indicates a short-lived impairment of perceptual/cognitive skills associated with their more stressful childbearing experience.

Adult↗
PubMed1988

Cerebrohepatorenal syndrome of Zellweger: a peroxisomal deficiency disorder. Case report and review.

The cerebrohepatorenal syndrome of Zellweger (CHRS) is a rare, fatal disorder in newborn infants. Recent research points to a primary absence of tissue peroxisomes, with resulting biochemical defects, as the basic pathology of the condition. We report on an infant with classic neurological and dysmorphic features of CHRS. Increased serum levels of pipecolic acid, bile acid precursors and very-long-chain fatty acids (VLCFA) together with total histological absence of liver peroxisomes confirmed the diagnosis. To our knowledge, this is the first case in Israel to be fully documented by biochemical and ultrastructural techniques. A high index of suspicion is essential among clinicians if further cases are not to be overlooked.

Facial Bones↗