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Biomedical subjects

A I Chasens

Publications and source records attributed to A I Chasens.

At least 19 recordsLinked to original sources

Controversies in occlusion.

The tissues and structures of the stomatognathic system adapt in different ways but in a coordinated manner to functional forces. This adaptive capacity differs from individual to individual and tends to cloud the picture as to how these mechanisms function. This leads to many areas of disagreement as to the role of occlusal trauma in the etiology of periodontal disease; the importance of centric, bite collapse versus arch collapse; the role of incisal guidance in maintaining occlusal stability; canine protected-guided occlusion versus group function; the use of appliances in occlusal therapy; prophylactic versus interceptive occlusal adjustment; and the role of bruxism and other parafunctional habits in occlusal trauma. An attempt is made in this article to clarify these issues.

Animals

Rapid loss of alveolar bone associated with nonprecious alloy crowns in two patients with nickel hypersensitivity.

In recent years there has been a dramatic increase in the use of nonprecious alloy and porcelain crowns in clinical dentistry. The alloy in these restorations frequently contains a high percentage (greater than 70%) of nickel. Most cases of metal hypersensitivity are related to nickel, and clinical manifestations of the hypersensitivity are the result of a cellular (T lymphocyte) immune response. In this report, we review the cases of two women who demonstrated significant loss of alveolar bone about nickel-rich nonprecious alloy and porcelain crowns. The loss of alveolar bone occurred within 18 months after placement of the restorations. Both individuals displayed a positive patch test to a nickel preparation. These findings suggest that a Type IV hypersensitivity reaction may have accounted for the rapid loss of alveolar bone. Though the majority of individuals treated with nonprecious alloy and porcelain crowns apparently tolerate these restorations quite well, greater care is urged in case selection.

Adult

Role of the polymorphonuclear leukocyte in periodontal health and disease.

This review presents evidence for lysosomal enzymes being at least partly responsible for the tissue destruction seen in periodontal disease. However, many other inflammatory and immunologic mechanisms have been identified that can contribute to tissue destruction (Nisengard 1977). The relationship of PMN to the periodontal tissues is equivalent to the proverbial double-edged sword. The localized tissue destruction that may be due to the extracellular release of PMN enzymes in individuals with normal cell function must be weighed against the role of PMN in containment of gingival bacteria and their products. The consequences of qualitative and/or quantitative abnormalities of neutrophils are far more undesirable for the periodontium. It therefore seems logical to propose that the role of polymorphonuclear leukocytes in the gingival tissues is primarily a defensive one. The presence of neutrophils in the gingival crevice has been shown to reflect the inflammatory condition of the tissues. Due to their availability, it may prove beneficial to use gingival crevicular PMN activity as a reliable clinical index of disease activity. The development of appropriate tests to measure PMN may eventually lead to better diagnostic criteria, including the definition of active versus inactive disease.

Animals

Keyes technique.

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Bicarbonates

Chronic pemphigus vulgaris of the gingiva. A case report with a 6-year follow-up.

Since the initial lesions of pemphigus vulgaris often appear in the oral cavity, dentists have a major role in the recognition and diagnosis of this condition. The patient reported here was seen with a mild gingival form of the disease and has been managed successfully for the past 6 years without systemic steroids and with minimal topical steroid therapy. For most of that period he was managed without medication. Various aspects of the disease, including diagnosis, the significance of pemphigus antibodies and therapy are reviewed to provide a better perspective on this case.

Chronic Disease

Free soft tissue autografts. Hemostasis and protection of the palatal donor site with a microfibrillar collagen preparation.

The use of free soft tissue autograft procedures has been well established and documented. However, little attention has been devoted to the care of the donor site which most frequently consists of palatal mucosa. The purpose of this study was to evaluate the hemostasis and protection of the palatal donor site of free soft tissue autografts using a microfibrillar collagen hemostat preparation. Twenty healthy adult subjects were selected. Ten patients in the experimental group received the microfibrillar collagen hemostat as a dressing while the control group received a conventional dressing. The results demonstrated that 10 minutes after the split thickness mucosal grafts were removed, the mean volume of blood absorbed by the sampling technique was 0.96 ml in the treated wounds vs. 1.85 ml in the control. There were no apparent differences in the quality of healing or the pain perceived by the patients in the experimental and control groups. It was concluded that the microfibrillar collagen hemostat produced rapid and effective hemostasis and protected the denuded palatal donor sites obviating the need for a conventional periodontal dressing.

Adult

Association between ABO blood groups, HL-A antigens and periodontal diseases in young adults: a follow-up study.

Two hundred and thirty-eight Caucasians were studied for ABO blood typing and for HL-A antigens. The subjects were divided into normal, necrotizing ulcerative gingivitis, chronic gingivitis, periodontosis and periodontitis groups. Results showed the chronic gingivitis group was significantly different in ABO grouping than the control group with the gingivitis subjects having a larger percentage of AB types and a smaller percentage of O types. The periodontosis group showed a trend toward more A and B blood groups and a smaller percentage of O groups than the controls. Compared to the normal group there was a significant reduction in HL-A2 antigen frequency in the periodontitis groups and a trend in reduced frequency in the periodontosis group.

ABO Blood-Group System

The relationship between the mobility of human teeth and their supracrestal fiber support.

A method to study the relationship between the mobility of human teeth and their supracrestal fiber support was developed. The results of this study would indicate that: (1) The supracrestal fibers do not contribute significantly to the support of a normal premolar tooth. (2) As a human premolar tooth develops moderate to severe loss of osseous support, the relative contribution of the supracrestal fibers to the support of the tooth increases significantly.

Adolescent