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Biomedical subjects

A Hubens

Publications and source records attributed to A Hubens.

At least 37 records · Page 2Linked to original sources

Effect of cisapride on the post-cholecystectomy upper gastrointestinal transit time.

For the evaluation of postoperative upper gastrointestinal transit, the breath hydrogen test is a convenient method, which is simple but more reliable than the recording of clinical parameters such as bowel sounds. The test was used to study the effect of cisapride on the postoperative mouth-to-caecum transit time. Twenty patients undergoing cholecystectomy were tested pre-operatively and on the first postoperative day after having received either 10 mg of cisapride i.v. or matching placebo under double-blind conditions. The median preoperative transit time in the placebo group was 45 min, and the median postoperative transit time at least 3 h longer. The postoperative transit time after cisapride dosing was still longer than before the operation but was significantly (p = 0.02) reduced as compared with that after placebo administration.

Adult↗

Anterior gastric stapling combined with posterior truncal vagotomy: an experimental technique for gastric acid reduction.

An operative technique using a mechanical stapling device has been developed to simplify proximal gastric vagotomy. A series of gastric fistula dogs underwent posterior truncal vagotomy and anterior lesser curvature stapling. The basal and pentagastrin-stimulated acid secretion was measured before surgery and 2 weeks and 3 and 9 months after surgery. During the whole period, no change in body weight was noticed. Gastric acid secretion in dogs remained low and stable during the first year after the procedure.

Animals↗

Isolated unilateral adrenal hemorrhage after a motorcycle race.

A 19-year-old girl presenting with an isolated unilateral adrenal hemorrhage after a motorcycle cross-country race without evidence of direct trauma, is reported. The lesion was diagnosed by abdominal ultrasonography, and treated surgically by thoracolaparotomy. Recovery has resulted. A review of literature shows the rarity of the condition.

Adrenal Gland Diseases↗

Prevalence of Candida albicans in patients receiving total parenteral nutrition.

The prevalence of Candida albicans was quantitatively compared in 74 surgical patients during and after total parenteral nutrition (TPN). Suppression of oral food intake is probably responsible for the decrease of the C. albicans population in the mouth. On the contrary anal swabs were more often positive for C. albicans during TPN. This may be due to local conditions as was observed in a group of patients who were not given TPN but were also immobilized for a long period.

Adolescent↗

Spontaneous rupture of the cystic duct during pregnancy.

A patient with an acute abdomen during pregnancy is reported. It was due to perforation of the cystic duct by a cholesterol gallstone. A cholecystectomy and T-tube drainage resulted in recovery and normal delivery twelve weeks after operation. The presence of gallstones, their location at the weakest point of the cystic duct, and the possible hemodynamic changes (as there is a higher pressure in the vena cava) occurring during pregnancy, are discussed as possible causes of this acute abdominal condition.

Abdomen, Acute↗

Hepatic artery aneurysm: a pitfall in biliary surgery.

This paper describes a patient operated upon for gall-bladder and bile duct stones, who presented with an extrahepatic aneurysm of the main hepatic arterial trunk and with a central intrahepatic haematoma assumed to be caused by the rupture of an intrahepatic aneurysm or by secondary intrahepatic necrosis. Exploration of the bile ducts resulted in haemobilia. The presence of extrahepatic arterial collaterals precluded individualization of the left and right hepatic arteries and subsequent distal arterial ligation or partial hepatectomy. Ligation of the common hepatic artery, although initially successful, was insufficient to avoid a recurrent and fatal haemobilia.

Aged↗

The effect of Lord's procedure on anal pressure.

In this study, the authors recorded pre- and postoperative anal resting pressures in 28 patients with hemorrhoidal disease and in 32 controls. No significant difference was found between these two groups preoperatively. In the patient population anal pressure was significantly lowered following Lord's anal dilation treatment. No such pressure reduction was recorded after a standard St. Mark's hemorrhoidectomy. Finally, the authors confirm that anal pressure measurements record only the tonus of the sphincter apparatus and are not influenced by the volume of the hemorrhoidal masses themselves.

Anal Canal↗

Vaterian diverticula as a cause of acute pancreatitis.

The association of duodenal diverticula and pancreatitis is rare. Various types of such diverticula are reviewed, especially intra- and extraluminal Vaterian diverticula in which common and pancreatic duct terminate. The pathogenesis of the pancreatitis in case of interposed Vaterian diverticula is thought to be mechanical by means of the creation of a closed Vaterian pouch in which higher pressures produce reflux of bile and pancreatic enzymes. Two patients with this particular type of duodenal diverticula are presented.

Acute Disease↗

[Our experience of the Vest-Margulis test in the differential diagnosis of mechanical and paralytic ileus (author's transl)].

In order to evaluate the Vest-Margulis test in the differential diagnosis between mechanical and paralytic ileus a retrospective study was undertaken on 51 such tests performed before and after operation. Transit of gastrografin (Sodium amidotrizoate) through the caecum 4 hours after ingestion was controlled through roentgenograms. The diagnostic value of a positive test in pure paralytic ileus can be confirmed. Indeed 23 positive cases proved to have paralytic rather than mechanical ileus. On the contrary a negative test has no diagnostic value. Twenty-eight patients in which the contrast medium had not reached the caecum within 4 hours had either form of intestinal obstruction. The attention is drawn on the interesting therapeutic action of gastrografin in patients with a paralytic ileus and the simplicity of the investigation.

Cecum↗

[Late sequellae of a splenectomy (author's transl)].

This is the case of a patient who underwent splenectomy after traumatic rupture of the spleen. After the operation, while on parenteral feeding, the patient presented with fever and septicemia during approximately 2 months; no origin to this could be found. Two months after the accident the patient died of perforation of a subdiaphragmatic abscess into the stomach and the lung. The authors discuss the possibilities of coming to an earlier diagnosis. They recognize the necessity of a more aggressive attitude to establish the diagnosis.

Adult↗