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Biomedical subjects

A Hrycek

Publications and source records attributed to A Hrycek.

79 records · Page 5Linked to original sources
PubMedDate not supplied

Adherence of peripheral blood neutrophils in X-ray operators.

The studies were conducted among 39 people (29 women and 10 men) operating X-ray equipment in radiology institutes and comparisons were made in the following schemes: A/ Group of persons operating the X-ray equipment (39 persons) and control group (18 persons). B/ A subgroup of persons that had been operating radiology equipment for > 5 years (29 workers was separated) and the results were compared with those for the subgroup of persons working < 5 years (10 workers). C/ Among the workers a subgroup of women (29) was separated and the results were compared with those for the subgroup of men (10 men). The following investigations were carried out: 1./ The absolute number of neutrophils in peripheral blood. 2./ Neutrophil adherence to fibres. 3./ Evaluation of CD 11b/CD 18 adhesion molecules expression on the surface of neutrophils. 4./ Evaluation of fibronectin concentration in serum. In the group A of the employees examined who operated X-ray units compared with the control group, the statistically significant decrease in the percentage of peripheral blood neutrophils showing adherence was observed and statistically significant decrease in median value and decrease of "Peak" value from the curve of the CD 18 adhesion molecule expression was detected and amounted to respectively: 91.0 +/- 4.26% adhering neutrophils in workers operating X-ray units and 94.8 +/- 2.98% in control group; values of median 120 +/- 4 in workers and 123 +/- 3 in control group in logarithmic scale; values of "Peak" 120 +/- 4 in workers and 123 +/- 3 in control group in logarithmic scale. Our own testing results show that the adherence properties of the peripheral blood neutrophils taken from X-ray operators are independent of the length of employment period and of the sex of the persons tested.

Adult↗
PubMedDate not supplied

[Morgagni-Stewart-Morel syndrome in a young man].

A 32-year-old man is reported with the Morgagni-Morell-Stewart syndrome with hypertension, diabetes, obesity, emotional lability, irritability and thickening of the internal lamina of the frontal bone in radiogram, which is the phatognomonic sing for the syndrome. The syndrome is rarely observed in men. Hormonal determinations showed increased serum concentrations of prolactin and thyrotropic hormone.

Adult↗
PubMedDate not supplied

[Peripheral blood phagocyte count and ultrastructure of neutrophils in patients with hyperthyroidism and hypothyroidism].

The study was carried out in 80 women with hyperthyroidism (40 with Graves-Basedow disease and 40 with hyperactive nodular goitre) and in 30 women with primary hypothyroidism. In the group with hyperthyroidism the total leucocyte count and the absolute count of neutrophils in peripheral blood were lower than in controls. In the group hypothyroidism the absolute count of monocytes was higher than in controls. In both studied groups ultrastructural changes were noted in the cytoplasm of neutrophils.

Adult↗
PubMedDate not supplied

[Cytochemical studies of peripheral blood granulocytes of workers with occupational exposure to lead compounds].

In 50 workers of a non-iron metallurgic plant exposed in their work to lead and trace amounts of cadmium and zinc cytochemical reactions were carried out in peripheral blood granulocytes. The control group comprised 30 men. In the investigations the degree of intoxication with lead compounds and the effect of the length of exposure ion the cytochemical reactions were taken into account. It was observed in these investigations that chronic exposure to lead and trace amounts of the remaining elements caused changes in the activity of acid phosphatase, alkaline phosphatase, lactic dehydrogenase and MOP. In particular, a significant fall of MOP and acid phosphatase activity and increased LDH activity in subjects exposed to lead with biochemical evidence of lead absorption deserve attention. With longer exposure to lead the activity of MPO decreased in workers with evidence of lead absorption.

Acid Phosphatase↗
PubMedDate not supplied

[Evaluation of phagocytic and bactericidal activities of neutrophils in peripheral blood of patients with anemia due to iron deficit].

Phagocytic and bactericidal properties of neutrophils have been evaluated in 20 women with anemia due to iron deficit. Twenty healthy women in corresponding age and domicile served as a control group. No statistically significant difference in both phagocytic and bactericidal properties of peripheral blood neutrophils have been noted in both groups. A decrease in plasma bactericidal activity has been sen in patients with anemia due to iron deficit. It may be one of the causes of increased susceptibility to infections noted in patients with plasma iron deficit.

Adult↗
PubMedDate not supplied

[Study of nitroblue tetrazolium reduction by granulocytes in workers handling x-ray equipment].

In 44 persons (25 women and 15 men), workers handling X-ray equipment in X-ray laboratories the ability was studied of nitroblue tetrazolium (NBT) reduction by neutrophils. The obtained results were compared with a control group. Besides that subgroups were isolated taking into account the sex of the studied subjects and duration of their work with X-ray equipment (over five years and below five years). In the workers handling X-ray equipment and in the isolated subgroups of women and men, the index of spontaneous NBT reduction turned out to be statistically significantly higher than that in the control group. In the group of studied workers the index of latex-stimulated NBT reduction was statistically significantly lower than that in the control group. Taking into account the duration of work with X-ray equipment in the subgroups of women and men working for over five years, the lowest index of phagocytes was noted. On the basis of the obtained results the following conclusions were formulated: 1. In workers handling X-ray equipment disturbances occur of peripheral blood neutrophil metabolism assessed in the NBT test. 2. Neutrophil phagocytic activity is weakened in persons working over five years with X-ray equipment.

Adult↗