The serum pregnancy associated alpha 2-glycoprotein level in patients with nephrotic syndrome.
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Biomedical subjects
Publications and source records attributed to A Hirabayashi.
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To perform continuous ambulatory peritoneal dialysis (CAPD), a safe and easy bag exchange system must be established. The authors developed a new system called "Safedap" and applied it to clinical cases. Safedap consists of a bottom, a sleeve, a shell, and a lock-type connector. The bottom and sleeve are made into one unit with a preembedded sponge saturated with 10% povidone-iodine for disinfection and protection. Safedap was introduced to 23 patients who were observed for a period of 293 patient months. Sixteen patients used a standard spike and functioned as controls. Peritonitis rates were 1/73.3 patient months in Safedap (4 episodes in 3 patients) and 1/30.1 patient months in controls (10 episodes in 7 patients; p less than 0.05). Using life table analysis, the probability of a control being peritonitis free at 12 months was 0.63 versus 0.95 in those using Safedap (p less than 0.05). By allowing completion of bag exchanges safely and rapidly, Safedap is effective in reducing the occurrence rate of peritonitis.
A new sorbent, urethane sheet embedded with powdered charcoal (UPC, BESPORE), which had been developed for use in a temporary liver support system, has been clinically applied since 1984. This system consists of a UPC plasma-perfusion circuit (using a recirculation system) followed by a supplementary 0.8 L plasma exchange, using hemodialysis for the purpose of performing both removal and supplementary therapy at the same time. On average, approximately 40% of both bilirubin and bile acid are removed, with the osmolality gap reduced by 30%. This system is effective for prolongation of life in patients with chronic hepatic failure and those with acute hepatic failure that has become chronic. It can be considered an effective maintenance therapy for patients before liver transplantation.