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Biomedical subjects

A Hesse

Publications and source records attributed to A Hesse.

At least 127 records · Page 7Linked to original sources
PubMed1985

An evaluation of test sticks used for the measurement of the specific gravity of urine from patients with stone disease.

A test stick for the measurement of the SG of the urine of stoneformers was examined. In 230 spontaneously voided urines and 45 25 h-urines the SG was measured by the test stick and compared with urinometer measurements. The two methods showed a good correlation (r = 0.86). Due to the principle of reaction of the SG-teststick a direct relationship of the SG-values to the sodium concentration and to the ionic strength of urine was found. There is no correlation between the relative supersaturation of CaOx and the SG-determination (urinometer, test stick). The handling of the SG-test stick is simple and can be easily performed by the patient.

Calcium↗
PubMed1984

Immunologic response to the treatment of Ehrlich ascites tumor with titanocene dichloride.

After treatment of mice bearing Ehrlich ascites tumor (EAT) with titanocene dichloride, it could be shown (a) that all cured animals were able to reject EAT cells implanted subsequently and (b) that in the serum of these animals the contents of gamma-globulins was markedly increased, whereas after treatment with cis-platinum both the ability to reject EAT cells and the increase of gamma-globulins were less pronounced. It is supposed that the observed increase of gamma-globulins is due to a stimulated production of antibodies against EAT.

Animals↗
PubMed1984

Temporary threshold shifts after onset and offset of moderately loud low-frequency maskers.

Moderately loud low-frequency maskers produce temporary threshold shifts which oscillate for a few minutes in reproducible patterns not only after their offset, but also after their onset. The temporal variations of threshold show "bounces" similar to those found by Hirsh and Ward [J. Acoust. Soc. Am. 24, 131-141 (1952)] after the offset of very loud maskers. In the present paper, threshold shifts of up to 30 dB are reported for pauses of 3-min duration in continuous maskers. These effects could originate in the internal cochlear metabolism, the steady-state condition of which seems to be influenced by the moderately loud low-frequency tones.

Adult↗
PubMed1983

[Optimizing conservative urinary calculus expulsion].

A multicentric randomised and prospective study on conservative treatment of ureteric calculi had been performed. The frequency and transit time of spontaneously passing of the stones, side effects and cost of treatment have been compared under classic spasmoanalgetic therapy and a phytotherapeutic medicament (Urol). In the group with spasmoanalgetic therapy 85.5% of the stones passed spontaneously, in the group with Urol medication 89.3% of the stones. There was no significant difference concerning the transit time of stones between the two groups, but side effects and costs were less in the Urol-group.

Adolescent↗
PubMed1982

Incidence, Prevalence and mortality of urolithiasis in the German Federal Republic.

Two nationwide surveys were conducted in the German Federal Republic. An incidence of 0.54% and a prevalence of 4% were registered. The ratio of men to women for incidence was 2:1 and for prevalence 1:1. Stone prevalence increased from 1.28% to 6.79% with increasing age. The occupational groups mostly affected were pensioners (34.3%), housewives (23.5%) and employees (16.9%). In cities the prevalence rate was higher than in rural areas. In recent years the mortality rate had decreased.

Adolescent↗
PubMed1982

Circadian rhythm of lithogenic substances in the urine.

After determination of the lithogenic and inhibitory substances in serum and urine of 18 healthy control subjects and 20 patients with calcium oxalate urolithiasis on an uncontrolled diet, the alteration of the parameters while taking a standard diet was investigated. After attainment of a steady state, the investigations were performed over 48 h on 3-h aliquots of urine. Typical circadian rhythms were detected for all lithogenic parameters in the urine and normal ranges were established. This special investigation permits detection of "peaks" in the excretion of lithogenic substances which were masked in investigation of 24-h urine samples alone.

Adult↗
PubMed1982

Parathyroid hormone is normal in renal stone patients with idiopathic hypercalciuria and high fasting urinary calcium.

In a group of patients with idiopathic hypercalciuria and an increased fasting urinary calcium excretion we re-examined the question: does secondary hyperparathy-roididsm exist? Eight out of 51 patients with calcium renal stones had a high calcium excretion in both fasting and in 24 h urines. The carboxyl-terminal immunoreactive PTH (iPTH) values in these patients were 16 +/- 5 ngeq/ml (M +/- SD), no higher than the iPTH values in the other groups, e.g. normocalciuric patients had an iPTH of 23 +/- 8 ngeq/ml. The existence of secondary hyperparathyroidism in a subgroup of stone patients with increased fasting urinary calcium excretion is questionable.

Adolescent↗
PubMed1982

Epidemiology, Pathogenesis and diagnosis of calcium oxalate urolithiasis.

In the German Federal Republic, the incidence of urolithiasis is 0.54% and the prevalence is 4%. Calcium oxalate stones are to be expected in over 60% of the cases. Pathogenetic factors are discussed. It is demonstrated that the overconsumption of chocolate, rhubarb and spinach brings about risk situations for stone formation, while asparagus and tomatoes present no risk. The increased animal protein and alcohol intake may be the most important reasons for the accumulations of calcium oxalate stones. Beside the minimum investigation programme it is demonstrated by examples that recurrent stone formers need an extended investigation to find out more about the pathogenesis, in order to determine an effective treatment or to prevent recurrences.

Adult↗
PubMed1982

[Results of quality control surveys for urinary calculus analyses].

In 1980 and 1981, four quality control surveys for urinary calculus analyses were carried out, within the framework of external quality controls of the Deutsche Gesellschaft für Klinische Chemie. During these quality control surveys the participating laboratories received a total of 16 samples (eight pure substances and eight mixtures of two components), to be analyzed qualitatively and quantitatively. For the qualitative analyses, a laboratory could provide simplified descriptions of the analytes - for example, without stating the number of molecules of the water of crystallization; or, to the extent permitted by the mode of analysis, the exact chemical composition could be presented. Of 1283 analyses, 818 (64%) attained the goals of the simplified analysis. The most frequent errors in chemical analyses were false negative and false positive results for calcium oxalate, and false negative results for calcium phosphate. Laboratories using analysis by infrared spectroscopy also submitted the biggest proportion of incorrect analyses for these components. The most reliable results were produced by X-ray-diffraction: 86% of the results in this category represented correct differentiated analyses. The generally accurate results achieved by some participants using chemical analysis suggest, however, that - in addition to the principle of analysis used - the qualification of the operator is an important determinant in the reliability of the results.

Calcium Oxalate↗
PubMed1981

[Medicinal teas in the prophylaxis of urinary calculus. Effect of solubitrat on the excretion of lithogenic and inhibitory substances (author's transl)].

While adhering to a standardized intake of food and liquids the effect of Solubitrat medicinal tea was tested under hospital conditions on the important serum parameters for urinary calculus formation and on the excretion of lithogenic and inhibitory substances in the urine. No significant differences were found in the serum parameters and in the 24 hr urine between the control group and the trial group. Observation of the day and night rhythm in the urine of the test group showed a prevention of the otherwise normal excretion peaks of most parameters at night, in particular the Ca concentration showing a significant flattening. Solubitrat medicinal tea consequently reduces the risk of urinary calculus formation and can be recommended without restriction for the fluid supply in the prophylaxis of urinary calculus.

Adult↗
PubMed1981

Characterisation of urinary crystals and thin polished sections of urinary calculi by means of an optical microscopic and scanning electron microscopic arrangement.

The use of optical microscopy and scanning electron microscopy combined permits a more far-reaching investigation of a given specimen. The subsequent element distribution analysis (EDAX system) allows the determination of mixed phases, inclusions and single crystals. The instrument combination was successfully tried on urinary crystals and thin sections of urinary calculi. The description of some findings, with the aid of examples, explains the efficiency of the system in the expansion of urinary calculus analysis.

Crystallization↗
PubMed1980

[Prevention of urinary calculi by means of a benzbromarone-citrate combination].

The action of a benzbromarone citrate combination (Harolan) in the prevention of uric acid and oxalate stones was studied in 21 patients suffering from calcium oxalate stones. The investigation was carried out under standard diet to eliminate possible variabilities in the excretion of lithogenous and inhibitory substances due to individual eating habits. Under Harolan a significant reduction in the serum uric acid level as well as simultaneous elevation of the urine pH-value could be achieved, the latter resulting in improved solubility of uric acid, the excretion of which is increased during the first days of treatment. Neither in 24 hour urine nor in the circadian rhythm was the solubility curve for uric acid exceeded during the test period. Side-effects were not observed.

Adult↗