Biomedical subjects
A Henning
Publications and source records attributed to A Henning.
[Complications following cataract incision 1751].
In 1751 the oculist Joseph Hillmer was expelled as charlatan from Petersburg by an expert opinion, which was founded on 125 case reports on his Russian clients, amongst them 60 suffering from cataracts, which had been couched on 80 eyes. Beside 82% of failures these case reports on cataract-couching contain postoperative complications, epicritically symptomatic for today's clinical pictures, which have been etiologically unknown in 1751. At least five eyes suffered postoperatively blindness by supposed detachment of the retina. The experts believed Hillmer's unexact, rough handling of the cataract needle to have been the reason. No less than 18 cases were complicated post operationem by secondary glaucomata, which ended at least twice as absolute glaucoma. We also recognize acute glaucoma, caused by couching the cataract. Secondary glaucomata were associated with severe iridocyclitis. In three cases there are indications of sympathetic ophthalmia. The experts seem to have been well acquainted with that threat to the untreated second eye. We are enabled to recognize a vitreous hemorrhage and an abscess in vitreum. No less than 21 times the couched crystalline lenses had set up again, in one case repeatedly after having been couched a second time.
Radiation-induced effects in multiprogrammable pacemakers and implantable defibrillators.
Twenty-three multiprogrammable pacemakers and four implantable cardioverter defibrillators (ICDs) containing either complementary metal-oxide semiconductor (CMOS) or CMOS/Bipolar integrated circuit (IC) technology were exposed to 6-MV photon and 18-MeV electron radiation at various dose levels. Of the 17 pacemakers exposed to photon radiation eight failed before 50 Gy, whereas four of the six pacemakers exposed to electron radiation failed before 70 Gy. Photon scatter doses were well tolerated. For the ICDs detection and charging time increased with accumulated radiation dose, the charging time increased catastrophically at less than 50 total pulses delivered when compared with the charging time of six implanted ICDs. Sensitivity and output energy delivered by the ICD pulse were constant during the test. It was found that devices using the shorter channel length IC technology (i.e., 3 microns CMOS) were per se harder to ionizing radiation than the devices using larger channel length IC technologies (i.e., either 8 microns CMOS or combined 5 microM CMOS/20 V Bipolar). In fact, none of the devices based on 3 microns CMOS IC technology failed before 76 Gy, which is above the highest dose level (70 Gy) normally used in radiation oncology treatments.
[The effectiveness of oral and parenteral vitamin A doses in growing cattle with different vitamin A supplies].
The effect of one single oral or parenterally administered dose of 1 million IU vitamin A on the vitamin A depot in the liver and on blood plasma vitamin A concentrations was investigated in 3 individual feeding experiments with involvement of 18 and 24 calves or 24 fattening bulls. 50% of all animals in each of the 3 experiments received feed without any vitamin A through 108 or 112 or 209 days, prior to vitamin A administration, or received 10.000 IU/100 kg live weight and day. Parenteral vitamin A administration in either group yielded rise in blood plasma from 0.06--0.35 to 26.2--30.2 mumol/l, after 1 or 2 days. The maximum value measured after oral administration was 1.9 mumol/l. Most of the plasma values had returned to normal (0.6--12. mumol/l) within 14 days from administration. Oral and parenteral vitamin A doses, after 14 days, caused significant rise in vitamin A concentrations in the liver (from 15.5 to 82.5), with the increase resulting from parenteral administration (from 13.7 to 99.1) being clearly higher than that resulting from oral administration (from 17.3 to 65.9 mumol/kg fresh liver tissue). The same trends were recorded from recovery of vitamin A from the liver (26.8% after parenteral administration versus 15.0% in the wake of oral doses). Storage in and recovery from vitamin-A depleted animals were below values recorded from young cattle with sufficient vitamin A supply. These findings are likely to confirm that one single parenteral vitamin A administration was of clearly higher effectiveness, as compared to oral application.
Andrea Henning, B.C.'s new provincial nurse advisor. Interview by Bruce Wells.
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Tomographic localization of motion axes.
Localization of motion axes within joints and junctures in living humans has been carried out by means of roentgen stereophotogrammetry. Another technique is presented here, in which the localization of the axis is carried out by means of tomography. The field of application for this technique has been examined in a series of phantom experiments. It may be employed in certain situations where roentgen stereophotogrammetry is not useful. No other equipment is needed than a pluridirectional tomograph and conventional dark-room facilities.
Effect of intra-arterial CO2 insuffflation on occlusive arterial disease in the lower leg.
Twenty patients with a mean age of 79 years were followed over a period of 6 months after intra-arterial insufflation of CO2 in the lower extremity. All patients had severe peripheral occlusive arterial disease caused by atherosclerosis and were scheduled for amputation. A significant increase of the distal perfusion pressure was obtained in the majority of the cases resulting in pain relief and healing of ulcers and gangrenes.
Value of a follow-up study of recurrent carcinoma of the colon and rectum.
The results of our programmed follow-up study of patients with carcinoma of the colon and rectum have been disappointing. This is true also for those patients who have undergone resection with the intention of cure. This is mainly because of the discouraging results of our treatment of recurrent lesions. Chemotherapy or roentgen radiation has not regularly been used. The mean survival time has probably been prolonged in some single instances. Only three out of 36 are still alive. Oour negative results show that a follow-up study of this magnitude has been too extensive when the poor outcome is considered. We believe that a follow-up study of patients who have been operated upon for carcinoma of the colon and rectum is necessary but in a simpler form than we have done.
[Distribution of thallium in the organism of a pregnant domestic cat].
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[Congenital thoracic duct stenosis in a dog with ascites].
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