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Biomedical subjects

A Helmstädter

Publications and source records attributed to A Helmstädter.

16 recordsLinked to original sources
PubMed2003

The history of electrotherapy of pain--or: what Voltaren has to do with voltage.

To reasons not yet completely understood, the pharmaceutical trademark Voltaren or Voltarol refers to the Italian scientist Alessandro Volta (1745-1827) who played an important role in the history of electricity. It is shown that electrotherapy has been used for the treatment of pain, gout and rheumatic disorders from ancient times to the present day. This therapeutic attempt was also discussed in scientific literature in the late 1960s, the time Voltaren was under development. Therefore, it is suggested that the electrotherapy of pain in history is a background for chosing this trademark.

Electric Stimulation Therapy↗
PubMed2001

The history of electrically-assisted transdermal drug delivery ("iontophoresis").

The first proposals for the use of electric current in drug delivery date from the mid 18th century. Serious progress was made in the 19th century notably by Benjamin Ward Richardson (1828-1896), Hermann Munk (1839-1912), William James Morton (1846-1920), Stéphane Leduc (1853-1939) and Fritz Frankenhäuser (born 1868). Administration of metal ions as well as alkaloids was tried at that time. Until the early 20th century, current mediated drug delivery was known as "cataphoresis"; Frankenhäuser is said to have introduced the term "iontophoresis" before 1908. Recently, researchers talk about "electrically-assisted transdermal drug delivery". The technique was never widely adopted but always proved useful to some extent in solving particular drug delivery problems. At the dawn of the 21st century, attempts are being made to achieve iontophoretic delivery of peptides and proteins.

Administration, Cutaneous↗
PubMed2001

[Parenteral administration of formic acid in alternative medicine].

Treatment of rheumatic and other diseases through immersion in an anthill is reported in German folk medicine. In the first half of the twentieth century, the physicians Eduard and Egon Krull (1842-1914 and 1879-1936, respectively) as well as Albrecht Reuter (1863-1937) recommended injections of diluted formic acid to treat tuberculosis, gout, arthritis, renal disorders and other complaints. Between 1930 and 1960, more than 15 different commercial preparations were marketed, and Egon Krull invented a drug series called "Myrmekan". Formic acid inhalations were recommended by Sigmund von Kapff (1864-1946) at a time when the acid was rarely used in homeopathy. In the 1950s, the injection of formic acid was regarded as one of the most important procedures in alternative medicine.

Complementary Therapies↗
PubMed1998

[Not Available].

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Economics, Pharmaceutical↗
PubMed1997

[Equipment and stocks in a German hospital pharmacy in the 19th century].

Two inventories from the hospital pharmacy in Cologne, founded 1807, give insight into the equipment of such an institution in Germany during the nineteenth century. The lists dated 1818 and 1884 have been transcribed and are presented verbatim. Additionally, a stock list dated 1817 was investigated.

Equipment and Supplies↗
PubMed1995

[Instructions to German hospital pharmacists in the 19th century].

Nine instructions for hospital pharmacists from the nineteenth century were investigated. They show the pharmacist's responsibility for drug quality and the observance of all legal requirements. He had usually no economical competences. Laboratory investigations and food research were common pharmaceutical tasks. To a great extent, the pharmacist had to deal with accounting and book-keeping.

Germany↗
PubMed1994

[Not Available].

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Germany↗