Murine herpes simplex virus keratitis is accentuated by CD4+, V beta 8.2+ Th2 T cells.
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Animals↗
Biomedical subjects
A Heiligenhaus
Publications and source records attributed to A Heiligenhaus.
[Congenital lacrimal duct obstructions].
If typical congenital nasolacrimal obstruction symptoms occur during the first few days of life immediate treatment is necessary. At the latest within two weeks the benefits of medication and massages of the lacrimal sac should be exploited to treat these conditions. It should be pointed out in particular that persisting membranes may perforate spontaneously. Should this treatment fail, high-pressure syringing and probing with Bangerter probes under local anesthesia must be performed very early. Due to the fact that the less complicated high-pressure syringing is often unsuccessful it is followed without delay by probing. If the ophthalmic surgeon is skilled, proceeds with care, and observes certain technical details complications can be avoided. The treatment described only fails in exceptional cases.
Child, Preschool↗
Photodynamic therapy for choroidal neovascularization in patients with multifocal choroiditis and panuveitis.
PURPOSE: To evaluate the visual benefit of photodynamic therapy (PDT) with verteporfin in patients with choroidal neovascularization (CNV) secondary to multifocal choroiditis and panuveitis over a longer follow-up period. METHODS: A total of 14 eyes of 12 patients (mean age 34 years) with a classic subfoveal CNV (13/14) or juxtafoveal CNV (1/14) were treated with PDT. Visual outcome was assessed by best-corrected visual acuity (VA). Morphologic characteristics of CNVs such as localization, size, and activity were monitored by fluorescein angiography. RESULTS: Patients were followed for 3 to 45 months (mean 23 months). During this period, one to six PDTs (mean 2.4) were performed. At the time of the first PDT no acute inflammation was seen in the affected eyes. Improved or stabilized visual function (VA loss < or = 2 lines in the Early Treatment Diabetic Retinopathy Study chart) was observed in 71.4% of the eyes. A total of 78% of the eyes showed an inactive scar in the area of CNV after PDT. Treatment failure after PDT occurred due to uninfluenced CNV growth. No further complications were observed. CONCLUSIONS: PDT in subfoveal or juxtafoveal classic CNV secondary to multifocal choroiditis and panuveitis stabilized or improved VA in the majority of patients over a longer follow-up period. No risk factor for failed VA rehabilitation could be defined.
Adolescent↗