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Biomedical subjects

A Haug

Publications and source records attributed to A Haug.

At least 73 records · Page 4Linked to original sources
PubMed1979

Postmortem findings in three patients treated with intravenous fat emulsions.

Three patients died of intercurrent illness in relation to intravenous nutrition with fat emulsions (20% Intralipid). In two cases, postmortem findings showed milky white, shiny, clotted lumps in the heart, with a fatty acid composition resembling that of fat emulsions. In vitro investigations make it likely that fibrin deposits in hyperlipemic plasma composed the lumps. In two cases, 30- to 50-mu Sudan-positive accumulations were found in the small vessels of the lungs, the cerebrum, and the kidneys.

Aged↗
PubMed1977

ZETA-Potential and surface charge of Thermoplasma acidophila.

The surface charge density and the zeta-potential of Thermoplasma acidophila was estimated from microscopic electrophoresis experiments. The cells moved towards the positive electrode. The mobility remained constant from pH 2 to 5, and increased for pH values higher than 6. The mobility at pH 6 decreased dramatically with increased external Ca2+ concentration. At pH 2 and an ionic strength similar to that of the growth medium, the zeta-potential was about 8 mV, negative relative to the bulk medium; the surface charge density was 1360esu/cm-2 which corresponds to one elementary charge per 3500 A2.

Calcium↗
PubMed1976

The influence of borate and calcium on the gel formation of a sulfated polysaccharide from Ulva lactuca.

The water-soluble, sulfated polysaccharide isolated from Ulva lactuca, forms a soft gel when dialysed against sea-water, provided the polysaccharide concentration is 1% or higher and the pH above 7.5. The components of sea-water needed for this gel formation are boric acid and calcium ions. At concentration normally found in sea-water, neither borate nor calcium ions alone produce a gel. It is assumed that the gel formation involves the formation of borate-polysaccharide complexes leading to intermolecular linkages which are stabilized by calcium ions in an unknown manner. This assumption is supported by experiments with extraction of this polysaccharide from the dry seaweed and by the results obtained with the isolated polysaccharide. Agreement between these experiments leads to the conclusion that the sulfated polysaccharide (in vivo) most probably occurs as a gel stabilized by the borate and calcium ions in sea-water.

Borates↗
PubMed1975

Intracellular pH of Thermoplasma acidophila.

Thermoplasma acidophila, a mycoplasma-like organism, was grown at 56 degrees C and pH 2. The intracellular pH of this organism is close to neutral as measured by the distribution of a radioactive weak organic acid, 5,5-dimethyl-2,4-oxazolidinedione, across the plasma membrane. The cell can maintain the pH gradient when subjected to heat or to metabolic inhibitors. Our experiments seem to indicate that a major portion of the pH gradient is not maintained by active processes, but rather by a Donnan potential across the cell membrane.

Biological Transport↗
PubMed1975

Membrane properties of Thermoplasma acidophila.

Plasma membranes were isolated from Thermoplasma acidophila, a mycoplasma-like organism which grows optimally at pH 2 and 59 degrees. Cells in concentrated suspensions were lysed by titrating to pH 9.3. The membranes were purified by washing at pH 10 and centrifuging in a discontinuous sucrose gradient. Membrane purity was assessed by electron microscopy, determination of deoxyribonucleic acid content, polyacrylamide gel electrophoretic behavior. Gel patterns and amino acid composition of cells and membranes were found to differ significantly. The lipid contained small amounts of fatty acid esters and larger amounts of branched long-chain alkyl ethers.

Amino Acids↗
PubMed1975

Structural studies of the extracellular polysaccharide produced by the diatom chaetoceros curvisetus cleve.

Methylation studies and partial acid hydrolysis have been carried out on the extracellular polysaccharide produced by the diatom Chaetoceros curvisetus. The polysaccharide contains the sugars galactose, rhamnose, and fucose and is partially sulfated. The presence of fucose in both furanose and pyranose forms within one molecule is reported for the first time. The fucofuranose is present as end groups, 1,2-linked and as branch points. Fucopyranose is mainly present as branch points in the polysaccharide, some being 1,3-linked, and a small fraction as end groups. The main part of rhamnose is 1,2-linked and galactose is mainly 1,3-linked.

Fucose↗