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Biomedical subjects

A Harada

Publications and source records attributed to A Harada.

At least 307 records · Page 17Linked to original sources
PubMed1987

A new method for typing haptoglobin in bloodstains using immobilized allo A lectin.

Allo A lectin from the beetle, which is beta-D-galactose specific, reacts to haptoglobin but not to hemoglobin. The use of allo A-Sepharose for typing haptoglobin in bloodstains helped eliminate hemoglobin from the bloodstain extract and presented highly resolved haptoglobin patterns by disc gel electrophoresis. This method is simple and rapid for typing haptoglobin in bloodstains and can be easily used in forensic science laboratories.

Animals↗
PubMed1986

Two cases of gastric cancer-bearing double choledochus with ectopic drainage into the stomach.

Two cases of double choledochus with ectopic drainage into the stomach associated with gastric carcinoma were reported. The stomachs were resected because of the presence of cancer, and the orifices of the ectopic bile duct were found in the oral side of the lesions. In these two cases, hyperplasia of gastric foveolas and atrophy of fundic gland, with its cystic dilatation, were observed around the orifices. A possible correlation between direct flow of bile juice into the stomach through the ectopic bile duct and the development of gastric cancer was discussed. The literature regarding double choledochus was reviewed.

Adenocarcinoma↗
PubMed1986

[A case of pelvic arteriovenous malformation].

Congenital pelvic arteriovenous malformation (AVM) is an uncommon lesion. This disorder occurs in female frequently than in male. A 44 year-old male complained of right lower abdominal discomfort and hemorrhoids. He had neither history of abdominal trauma nor abdominal surgery. A pulsatile mass was palpable on rectal digital examination and bruit was heard at right lower abdominal quadrant. Pelvic computerized tomogram showed an abnormal mass with homogeneous density near the right side of the bladder. The mass was equally enhanced by the contrast medium. Digital subtraction angiogram revealed the pelvic AVM which originate from right hypogastric artery. Selective angiogram showed many feeding arteries and a dilated vein. Surgical procedure was performed with transabdominal approach because this AVM was localized. All feeding arteries and aneurysmally dilated vein were completely removed. Post operative course was uneventful. Follow up arteriogram after the surgery showed no further abnormal arteriovenous connections.

Adult↗
PubMed1985

Effect of blood pressure on the progression rate of renal impairment in chronic glomerulonephritis.

An effect of high blood pressure on the progression of renal functional deterioration was studied in 23 cases of chronic glomerulonephritis, which showed progressive renal functional impairments during the long-term follow-up period. The slope-of-regression line, which was obtained from the relation between reciprocal serum creatinine concentration (1/Cr) and observation time, was expressed as a progression rate and was evaluated on an association with blood pressure level. The progression rate was found to correlate significantly with the level of diastolic blood pressure (p less than 0.001). It is concluded that the elevation of blood pressure is one of the factors that contribute to the progression of renal functional impairment in chronic glomerulonephritis.

Adult↗
PubMed1985

[The clinical study of systemic hemodynamics after partial hepatectomy, with special reference to cirrhotic subjects].

To elucidate the pathophysiological role of partial hepatectomy on systemic hemodynamics, general hemodynamics were investigated in 29 patients pre and postoperatively. Twenty-five patients with smooth postoperative course were divided into two groups, non-cirrhotic (n = 15) and cirrhotic (n = 10). On the first postoperative day (p.o.d.), cardiac index (CI) increased significantly but arteriovenous oxygen content difference (C(a-v)O2) didn't increase in non-cirrhotics. While, increased in cirrhotics, CI increased only mildly and C(a-v)O2 increased. In both groups oxygen consumption (VO2) increased significantly. Since these characteristic pattern in cirrhotics were even clearer in patients with lower functional reserve of remnant liver, it was suggested that cardiac function was suppressed under decreased functional reserve of remnant liver. Four cirrhotics fell into hepatic failure during early postoperative period. On the first p.o.d., CI and C(a-v)O2 of these patients didn't increased, and VO2 decreased slightly. On the second p.o.d., CI increased but C(a-v)O2 and VO2 decreased extremely. It seemed likely that these disturbance of oxygen uptake and consumption affected function of remnant liver considerably.

Adult↗
PubMed1984

Renal amyloidosis associated with crescentic glomerulonephritis.

A case of renal amyloidosis coincidentally associated with crescentic glomerulonephritis is described. A 59-year-old female with 30 years' history of rheumatoid arthritis developed nephrotic syndrome followed by rapid deterioration of renal function. Among 28 glomeruli in a kidney biopsy specimen, glomerular amyloid deposition was present in 17 and crescent formation in 20. Only one glomerulus was free from amyloid deposition or crescent. The amyloid deposition was clearly demonstrated by congo red, thioflavin-T staining as well as electron-microscopic examination. Glomerular deposition of immunoglobulins and/or complements were not noted. While cyclophosphamide, dipyridamole, and heparin followed by pulse methylprednisolone were given, the renal function deteriorated progressively and dialysis was initiated. Renal function, however, recovered partially without medication after peritoneal dialysis of 3 months' duration. The second renal biopsy revealed the progression of glomerular amyloid deposition and the increase in fibrous component of crescent.

Amyloidosis↗
PubMed1984

[Diagnostic values of type III Procollagen N-terminal peptide and combination assay of type III procollagen N-terminal peptide with CEA and CA 19-9 in gastric cancer].

It is known that interstitial collagens are initially synthesized as precursors (procollagen), which possess extra peptide segments at both ends of the molecules. The authors attempted to detect the aminoterminal peptide of type III procollagen (type III-N-peptide) and also to measure the carcinoembryonic antigen (CEA) and carbohydrate antigen (CA 19-9) together in sera of patients with gastric cancer. The results showed that: (1) mean serum levels and positive ratios of the type III-N-peptide increased as the clinical stage of the patients with gastric cancer advanced; (2) serum levels of the type III-N-peptide were not correlated either with those of CEA or CA 19-9; (3) positive ratios of type III-N-peptide, CEA and CA 19-9 were 51.7%, 44.8% and 48.3%, respectively: (4) positive ratio in combination of the type III-N-peptide with CEA was 69.3% and that in combination of the type III-N-peptide with CEA and CA 19-9 was 72.4%. These results suggest that type III-N-peptide is available for diagnosis of gastric cancer and, that the combination assay of type III-N-peptide with CEA and CA 19-9 is more effective than a single assay for diagnosis.

Antigens, Neoplasm↗