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Biomedical subjects

A H den Ouden

Publications and source records attributed to A H den Ouden.

5 recordsLinked to original sources

The use of vibrotactile stimulation for determining sexual potency in the laboratory in men with erectile problems: methodological considerations.

Vibrotactile stimulation, when used in combination with visual sexual stimulation, has been shown to enhance erectile response in sexually functional men. The present study attempted to describe a diagnostic methodology, including the development and application of a new mini-vibrator, that might enhance penile response in men with erection problems. Tests on 78 men with either erectile dysfunction (ED), or a combination of erectile dysfunction and premature ejaculation (ED+PE), showed that vibratory stimulation together with an erotic video (EV+VT), produced greater penile response than the erotic video alone (EV). The new mini-vibrator was more effective than a previously used model, and produced clinically significant increases in erectile response in ED+PE men. In addition, the enhancing effect of the combined stimulation on self-reported penile response was greater when it followed EV than when it preceded it. The use of vibrotactile stimulation and visual sexual stimulation together may therefore assist in determining the potential sexual potency of men experiencing erection problems during the process of differential diagnosis.

Ejaculation↗

A new instrument for the measurement of forces on beds and seats.

Knowledge of the interaction of forces between persons and the bed in which they lie or the seat on which they are sitting, provides an insight into the loading of their muscles, bones and soft tissue. To determine the total forces on the body-supporting surfaces (backrest, seat pan, foot rest) resolved in components perpendicular and parallel to these surfaces a new instrument has been developed, with which the forces perpendicular and parallel to three different freely adjustable body-supporting surfaces can be registered. During the first measurements the forces on a bed were measured when a person sits in a bed with the backrest at an angle of 45 degrees to the horizontal and the mattress horizontal. The measurements on a healthy population (mean mass = 77 kg, SD = 11 kg) showed an accuracy of +/- 10N. In this position the mean shear force on the seat pan was 97 N.

Beds↗

Computer-controlled wheelchair ergometer.

A new wheelchair ergometer has been designed in which a combination of realistic simulation of wheelchair propulsion--with adjustable parameters for rolling resistance, air drag, wind speed and slope--and force measurement has been realised. The static solution enables the measurement of physiological and kinesiological parameters. All data from force transducers in seat and backrest, torque transducers in the wheels and force transducers in the wheelframes as well as the acquired speed are sampled in a data-acquisition system. An offline curve processor allows the acquired data to be processed with standard or custom-programmed routines. Preliminary results have been added and are discussed.

Engineering↗

The Rotterdam teletransducer. A telemetric device for measuring epidural pressure.

A discussion on the clinical value of telemetric measurements of intracranial pressure is presented. The technical improvements of an earlier described implantable epidural transducer are reported. Furthermore, the results are given of an in vivo study in dogs of the relation between epidural pressure as measured by this device and ventricular fluid pressure for variable physiologic conditions. An evaluation of the implantation technique is included and a justification for the selection of the constituting materials is given. Clinical results obtained in a patient are illustrated.

Animals↗

Long-term intracranial pressure monitoring.

Continuous or intermittent measurement of intracranial pressure (ICP) is important in patients at risk for raised ICP. Indications exist for short- and long-term measurements. The various methods used for short-term monitoring are discussed with their relative advantages and disadvantages. For long-term measurements of ICP use of a completely implantable telemetric epidural pressure transducer is indicated. No such device is commercially available. We have developed an inexpensive passive telemetric transducer for this purpose. Results obtained up till now have demonstrated its reliability for measurements of two to three months duration. The life span of the device is limited by degrading of the epoxy utilized for sealing of the titanium pressure sensing part to the radiolucent ceramic cap of the transducer, causing leakage of water into the transducer and false low measurements. Because of these problems new hermetic sealing techniques were tested. Both active metal brazing and glass bonding yielded good results and hermetic sealing could be obtained. The metal to ceramic bonding presented is generally applicable within the design of implants. Besides the technical progress reported, the experience with clinical use in 12 patients is presented.

Brain Injuries↗