Biomedical subjects

A H Robins

Publications and source records attributed to A H Robins.

35 records · Page 2Linked to original sources

PubMed1976

Are stroke patients more depressed than other disabled subjects?

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Aged↗

PubMed1976

Depression in patients with Parkinsonism.

Forty-five patients with parkinsonism were carefully matched for age and sex with 45 chronically disabled control patients with a significantly more severe grade of physical handicap. Depression was measured by the Hamilton Rating Scale, and it was found that the parkinsonian group was very significantly more depressed than the control group (p less than 0-0001). Depression scores in both groups were unaffected by the patients's sex or by the severity of the disability. Analysis of the individual ratings of the Hamilton Scale showed that parkinsonian patients had significantly higher scores on items relating to suicide, work and interests, retardation, psychic anxiety, general somatic symptoms, and loss of insight. It was concluded that patients with parkinsonism suffer a degree of depression which cannot be solely a reaction to the stress of physical disability. This finding is discussed with reference to the monoamine hypothesis of depressive illness.

Aged↗

PubMed1975

Melanosis after prolonged chlorpromazine therapy.

The effect of prolonged treatment with chlorpromazine in high dosage, on skin melanin, was measured by reflectance spectrophotometry. Whites and Blacks of both sexes were tested in this study which compared 201 chlorpromazine-treated, chronic psychiatric patients (predominantly schizophrenics) and 161 controls. The treated patients generally had significantly higher concentrations of melanin in the skin than the controls. These differences were particularly marked in the female groups and in the exposed areas of the White groups. The aetiology of the melanosis is discussed.

Black or African American↗

PubMed1974