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Biomedical subjects

A H Robb-Smith

Publications and source records attributed to A H Robb-Smith.

At least 19 recordsLinked to original sources

Osler's changing influence. Based on the Osler oration given at the Royal College of Physicians in 1990.

Over 20 years in North America William Osler transformed the pattern of medical education for both undergraduates and specialists. He wrote a textbook that not only was a stimulus to medical students and young doctors, but also inspired the railway baron J D Rockefeller to devote his wealth to the advancement of medical research and education. He encouraged the creation of medical associations and societies because he believed, rightly, that these enhanced not only the quality of medicine but also the relationship of the members of the profession, one with another. He provided a great library of medical history and medical biography which has been and will be an inspiration for years to come. In the 15 years Osler spent in England he created a school of medical science which has continued to burgeon and has formed a foundation for a great clinical and research medical school. He inspired the creation of the post-graduate centres associated with the general hospitals in every town throughout the country; he provided material for a biography which has inspired medical students and practitioners, who now realise that medicine is primarily about sick people, not disease; and he directed another great benefactor, Lord Nuffield, to devote his riches to many aspects of medicine.

Education, Medical

Osler's robes.

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Canada

Osler's influence on haematology.

Osler's influence in haematology was twofold: as an original observer both in the laboratory and the ward, and his encouragement of the establishment of clinical laboratories with the consequent development of clinical and laboratory haematologists. In 1870, when Osler entered McGill Medical School at the age of 21, he was already an experienced microscopist from his school days, but now his interest shifted from pond life to parasites and clinical microscopy. His post-graduate year with Burdon-Sanderson was to have been a study of leucocyte function, but instead came his research on platelets, continued and expanded when he returned to Montreal in 1874, together with much of his laboratory haematology--his comprehensive studies of pernicious anaemia and work on leukaemia, Hodgkin's disease etc. The move to Philadelphia in 1884 saw the establishment of a clinical laboratory, work on malaria, arsenic in anaemia and the blood disease chapter for Pepper's System. At Baltimore he had a rewarding clinical microscopy department, distinct from Welch's Institute, and this is the period, continued at Oxford, of Osler's accounts of clinical syndromes--polycythaemia, telangiectasia, mastocytosis and 'splenic anaemia'.

Blood Platelets

Medical logic.

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Education, Medical

Atypical multicentric reticulohistiocytosis with paraproteinemia.

Two women had multiple subcutaneous nodules that showed features of multicentric reticulohistiocytosis (MR). Neither had joint symptoms. Both had a raised erythrocyte sedimentation rate, an immunoglobulin G paraproteinemia, and raised levels of nonhepatic serum alkaline phosphatase. The skin lesions have been followed up, using light and electron microscopy, immunoperoxidase, and histochemical methods. The material in the giant cells stained positively for gamma heavy chain determinants: the light chain type in each case was that of the paraprotein. An attempt to reproduce the skin lesions in one patient by intradermal injection of her paraprotein failed.

Aged

Lennert lymphoma.

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Hodgkin Disease