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Biomedical subjects

A Gustafsson

Publications and source records attributed to A Gustafsson.

136 records · Page 8Linked to original sources
PubMedDate not supplied

Low HTLV-1 seroprevalence in endemic tropical spastic paraparesis in Ethiopia.

Tropical spastic paraparesis (TSP), a chronic progressive myelopathy, occurs in Ethiopia in epidemic form as neurolathyrism, while the endemic form has remained obscure. We describe the clinical features of 22 patients with TSP and the results of screening for HTLV-1 in these patients, 26 patients with other neurological disorders, 14 patients with leukaemia and 66 blood donors. The major manifestations in the patients with TSP were weakness and spasticity of the lower limbs with upper motor neurone signs and minimal sensory loss and bladder dysfunction. Two patients with TSP (9%), 2 patients with other neurological disorders (7.7%) and one patient with leukaemia and deafness were seropositive for HTLV-1. All the 66 blood donors were seronegative. Our results suggest that HTLV-1 may not play a major role in the pathogenesis of TSP in Ethiopia.

Adolescent↗
PubMedDate not supplied

A clinical attempt to avoid hyperacute rejection by F (ab') 2 organ pretreatment.

An attempt was made to, in a controlled study, avoid hyperacute rejection by pretreatment of a renal graft pepsine digested anti-donor antibodies. It turned out to be unsuccessful, but there were some indications that the chain of events that leads to the destruction of the graft was delayed for some hours. There may be several reasons for this failure but we think it is possible to improve this method even if its importance in clinical use is still doubtful.

Adult↗
PubMedDate not supplied

Transplantation of a duct-ligated pancreatic allograft to a diabetic patient.

A 52-year-old man with an extremely instable insulin-treated diabetes mellitus, were transplanted with a duct-ligated pancreatic segment from a brain-dead donor. The graft showed immediately a satisfying endocrine function. The blood glucose levels were normalized and no exogenous insulin was administered. After five days a clear fluid with high contents of protein and high concentration of amylase started to drain from the wound. The drainage ceased spontaneously after 30 days. On day 41 after transplantation, the function of the graft suddenly stopped. At exploration, the graft was found thrombotized but with a well preserved architecture, and the oversewn end of the graft was intact. The patient is back on insulin treatment, and he is in the same condition as before the transplantation.

Amylases↗