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Biomedical subjects

A Guijarro Morales

Publications and source records attributed to A Guijarro Morales.

At least 19 recordsLinked to original sources
PubMed1991

Zinc levels after intravenous administration of zinc sulphate in insulin-dependent diabetes mellitus patients.

Diabetic patients commonly have increased urinary excretion of zinc, although blood concentrations may be normal, lowered, or raised. We analyzed zinc levels in plasma and urine after an intravenous overload of zinc sulphate (8 mg) in 22 patients with insulin-dependent diabetes mellitus (IDDM) and 22 healthy individuals. No significant differences were found in basal levels of serum zinc in either group (111 +/- 29 micrograms/dl in IDDM vs 119 +/- 19 micrograms/dl in controls), although urinary excretion of zinc was significantly raised in diabetics (1396 +/- 622 micrograms/24 h) versus controls (611 +/- 235 micrograms/24 h). After zinc overload, both serum and urinary levels of this element varied between the two groups. Serum zinc in IDDM patients initially increased more markedly, and subsequently showed a more significant decline, than in controls. Urinary zinc levels in IDDM patients, in contrast to control values, showed no increase after overload. These alterations in serum and urinary zinc concentrations suggest that our diabetic patients may be zinc-deficient.

Adult↗
PubMed1990

[Acute mountain sickness].

Acute mountain sickness is a pathologic reaction as a result of bad adaptation to high altitudes (greater than 2.500 meters). The main symptoms are headache, nausea, vomits, and insomnia. When severe it can produce oliguria, retinal hemorrhage, ataxia and sometimes coma. Its etiology is not well known. It is considered that the first producer factor of the disease is tissular hypoxia secondary to low partial oxygen pressure existing in areas of high sea level. The treatment consists of descent and the use of dexametasone and acetazolamide.

Acute Disease↗
PubMed1980

[False diagnosis of myocardial infarction due to inversion of the electrocardiographic leads in the right limbs (author's transl)].

An abnormal ECG suggested the diagnosis of myocardial infarction in a 65-year-old man who had suffered a transient chest pain. When the patient was admitted to the Hospital a new ECG and biochemical enzymes were normal, but and identical pathologic ECG was registered following inversion of the electrocardiographic leads in the right superior and inferior extremities. A prospective study of 160 adult patients has demonstrated that inversion of the leads in the right limbs frequently causes the appearance of pathologic Q waves (37.14 percent) and ischemic T waves (51.22 percent), especially in lead I and aVL. Number of pathologic Q and T waves may vary when they are present in the basal register, but we never observed their disappearance in all the precordial lead series. A constant finding was the marked low voltage of P, QRS and T in lead II due to the "distance" of the electrocardiographic leads right leg-left leg. Technical recognition may be difficult because P waves and QRS complex are frequently negative or isoelectric in aVR.

Aged↗
PubMed1979

[Heart function and phonomechanocardiography (author's transl)].

The phonomechanocardiographic parameters most closely associated with heart failure are reviewed and a critical judgement is made of the method. The conclusion is drawn that phonomechanocardiographic measurements help to establish approximate limits of functional normality in cases of moderate abnormality. When acute phonomechanocardiographic alterations appear following infection or toxic heart disease or the use of potentially cardiotoxic drugs, the diagnosis of miocarditis can be made on an objective basis. To control the clinical course of heart failure the following parameters are useful: variations in the period of expulsion, "a" and "telediastolic" indices of the apexcardiogram, and the expulsion period/pre-expulsion period and expulsion period/systolic isovolumetric phase coefficients. Although phonomechancardiography lacks exact biological precision, it represents a rational and no invasive method for estimating heart function. It provides a means for recognizing diverse functional anomalies at their onset and for controlling their development. It thus helps in choosing adequate preventive and therapeutic measures to keep an early functional miocardial disease from becoming a serious case of heart failure.

Evaluation Studies as Topic↗