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Biomedical subjects

A Grosmanová

Publications and source records attributed to A Grosmanová.

9 recordsLinked to original sources

[Effect of birth weight on neonatal and maternal morbidity in expectant management of post-term pregnancy].

OBJECTIVE: In the retrospective study to evaluate whether the number of newborns over 4000 grams weight is greater under expectative management of post-term pregnancy and explain its influence on perinatal and maternal morbidity and mortality. DESIGN: Retrospective study. SETTING: Gynaecology and Obstetric Clinic, Medical Faculty, Masaryk University, Brno. METHODS: Two groups were compared. Group I includes 1906 women, who delivered in the year 1996 under the active management of the post-term pregnancy with induction of labour in the 41st week. Group II includes 2008 parturients who delivered under the expectative management of the post-term pregnancy with induction of labour at the end of 42nd week. Perinatal mortality, brachial plexus injuries, clavicle fractures, Caesarean section rate for cephalopelvic dysproportion and injuries in mothers were evaluated. Students T test and chi square test were used for statistical purposes. RESULTS: In the group with expectative management of the post-term pregnancy there was significantly higher number of newborns over 4000 grams. Perinatal mortality and morbidity did not differ between the two groups. There is no difference in maternal morbidity as well. CONCLUSIONS: Our results of expectative management in post-term pregnancies with newborns over 4000 grams did not confirm our worries about higher morbidity both in newborns and mothers. There is no need to consider the expectative management of the post-term pregnancies to be dangerous.

Birth Injuries↗

Mevalonic aciduria.

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Child, Preschool↗

[Initial clinical experience with the use of 31P MR spectroscopy in the examination of children with neuromuscular diseases].

31P MR spectroscopy (MRS) was used to investigate neuromuscular diseases of different origin in 35 patients, mostly children. After elaboration of the procedure of MR examination and evaluation of results the method of pattern recognition analysis was used. According to the results of 31P MR spectroscopy patients can be divided into three groups. Group A comprises patients with severe muscular lesions such as Duchenne dystrophy. The second group B is characterized by milder atrophic changes of muscle fibres. The third group comprises obscure cases. The 31P MRS method was also used for investigating the development of the disease in time--a drop of parameter PCR/Pi corresponds to a deterioration of the clinical condition of patients from group one. Maintenance of approximately the same values was observed in group B. An increase of PCR/Pi was also observed during administration of Prednisone in patients with child polymyositis.

Adolescent↗