Search PubMed⌕ Search

Biomedical subjects

A Graziottin

Publications and source records attributed to A Graziottin.

36 records · Page 2Linked to original sources
PubMed1992

[Treatment of psychogenic impotence].

Individual, marital or familiar problems, life circumstances, lack of libido, anxiety or sex identity fragility or immaturity may determine or make worse the erectile deficit. A thorough diagnostic work up is essential for the prognosis and the choice of the more fitting therapy. Emotional and cognitive understanding of the psychogenic background of the symptom is combined with behavioral therapy based on modern principles of neuroriabilitation.

Erectile Dysfunction↗
PubMed1984

[Antineoplastic agents and pregnancy].

The current impossibility of establishing a definite causal relationship between the administration of antineoplastic drugs before and/or during pregnancy and possible modifications of the gestational attitude in the treated women is discussed after a review of the Literature. The data till now reported are often deficient as far as concerns the evaluation of either the fetal, perinatal and post-natal parameters and the past and current reproductive performance of the patients on study. The need for strict methodology in the study and report of feto-maternal parameters to provide a comprehensive answer to the questions raised by the use of antineoplastic drugs before and/or during pregnancy is discussed in detail.

Abnormalities, Drug-Induced↗
PubMed1984

Plasma prolactin in women with mastodynia.

Plasma prolactin was measured by radioimmunoassay during the luteal phase in 22 patients affected by moderate or severe mastodynia and results were compared to those of 43 control subjects. No consistent changes were seen during the course of the luteal phase in either group. No significant differences were noted between the prolactin levels of the two groups. No association was found between moderate or severe mastodynia and variations of plasma prolactin levels.

Adult↗
PubMed1983

Non mutilant radical vulvectomy vs radical vulvectomy.

20 women, matched for age, site of primary tumor, histotype and stage, have been selected among patients affected with vulvar carcinoma for a study comparing classic radical vulvectomy vs "non mutilant" radical surgery. Detailed results actually available are discussed, showing that "non mutilant" technique gives results comparable to classic radical vulvectomy in terms of survival and recurrence rate; with minor functional and aesthetic damage, minor side effects and shorter post operative course.

Adult↗
PubMed1982

Use of intramyometrial injection of prostaglandin F 2 alpha in the management of intractable hemorrhage due to uterine atony.

Prostaglandin F2 alpha, in doses varying from 1 to 5 mg was injected transabdominally, transvaginally or intraabdominally (during caesarean section) into the myometrium in ten patients affected by metrorrhagias not responsive to conventional uterotonic drugs. In all cases but one the result was excellent. Important side effects were observed in only one patient, because of the inadvertent intravascular injection of 5 mg Prostaglandin into the endocervix. An adequate treatment of this patient brought her to complete recovery in a short time. According to our experience, the intramyometrial injection of PGF2 alpha, in doses varying from 1 to 2 mg, is a simple, safe and effective method in the control of severe hemorrhage due to uterine atony not responding to conventional treatment.

Adolescent↗
PubMed1982

Introduction to chemotherapy and antineoplastic pharmacology in breast cancer.

Tumor cell biology and growth-kinetics of human breast cancer are reviewed with reference to the different action mechanisms of main antitumor drugs. Particular emphasis is given to pharmacokinetics, dosage, mode of administration, effectiveness and side-effects of drugs most commonly used in breast cancer. The importance of tumor Estrogen and Progesterone Receptor assay for the therapy planning is considered and a short review of estrogens, androgens, progestins, antiestrogens, corticoids and aminogluthetimide is presented. The rationale for combined chemotherapy and/or hormonotherapy in breast cancer is finally discussed.

Antineoplastic Agents↗
PubMed1982

Epidemiology of nipple discharge.

The Authors report their personal observations of nipple discharge in gynecologic patients admitted to the Obstetric and Gynecologic Department of Padua University or applying to the Senologic Diagnostic- or Endocrinology-Departments of the same. After dividing breast secretions into two groups - the neuroendocrine and the strictly mammary ones - the Authors discuss their etiopathogenesis, incidence, and clinical significance (mainly as to their possible association to breast malignancies), and present their personal results. At the end, a careful examination of all nipple discharges is recommended, which should include, besides cytological evaluation, a complete assessment of the neuroendocrine function and a watchful investigation of local breast conditions.

Adult↗
PubMed1981

Bromoergocriptin therapy in eumenorrhoic patients presenting galactorrhea.

Eleven eumenorrhoic patients presenting galactorrhea were subjected to a three-month Bromoergocryptin therapy (2.5 mg/os/die). Prolactin Circadian Rhythm, performed on all patients, showed four hyper and seven normoprolactinemic cases. The mammary condition was studied, before and after treatment, through clinical examination, mammary cytology and thermography. Hyperprolactinemic patients responded positively to the therapy, showing subjective, clinical and thermographic improvement. Conversely, normoprolactinemic patients, though showing a noteworthy improvement of symptomatology and galactorrhea, did not respond equally well from the objective and thermographic points of view.

Adult↗
PubMed1981

Proposal of diagnostic approach in mammary pathology.

The Authors, on the basis of the literature and their own experience, propose a diagnostic schedule for detection of breast disease based on integrated thermography, diaphanoscopy, echography and mammography.

Biopsy, Needle↗
PubMed1981

Inadequate luteal phase and benign breast disease.

The Authors compare E2 and Progesterone plasma levels in the luteal phase of twelve normally menstruating women whose basal body temperature curves were biphasic and in which breast micronodularity and mastodynia were present, with those of ten breast disease-free controls. The significant difference (p less than 0.001) found in Progesterone levels gives strength to the opinion that Progesterone supply therapy can effectively improve both mastodynia and the clinical picture objectively documented.

Adult↗
PubMedDate not supplied

Clinical approach to dyspareunia.

Dyspareunia needs to be addressed from an integrated patient-centered perspective. This review analyzes the organic causes of pain during intercourse. Factors that are often underevaluated in the clinical setting include hormonal, inflammatory, muscular, iatrogenic, neurologic, vascular, connective, and immunitary causes. Psychosexual factors, such as vaginismus, loss of libido, arousal disorders and sexual pain-related disorders, often overlap. A preliminary clinical approach aimed at integrating different biological and psychosexual etiologies in a comprehensive manner is discussed in this article.

Adult↗
PubMedDate not supplied

Vulvodynia: the challenge of "unexplained" genital pain.

Vulvodynia is a clinical syndrome that may include unexplained vulvar pain, sexual dysfunction, and psychological disability. It is a multifactorial syndrome that should be diagnosed, if possible, with an intradisciplinary approach. This article discusses the diagnosis and treatment of vulvodynia, starting with a summary of the complex nervous system within the pelvis. Different clinical pictures and different subtypes of the syndrome have been described in order to identify the etiologic aspects that are essential for diagnosis and subsequent treatment. Clinical evaluation should stress attention to detailed "pain-mapping" and evaluation of past and present history. The gynecological examination should be an overall patient evaluation, incorporating global physical impression, change in posture due to pain and careful examination of the pelvic floor. Examination of the pelvic floor is frequently omitted. Leading to an incorrect diagnosis of psychogenic pain. Such a misdiagnosis can result in the dismissal of appropriate treatment. Proper evaluation requires a comprehensive, multidisciplinary approach that includes medical, rehabilitative, and psychological issues.

Adult↗