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Biomedical subjects

A Gilloz

Publications and source records attributed to A Gilloz.

At least 37 records · Page 2Linked to original sources
PubMed1986

[Cancer of kidney with venous invasiveness: prognosis. Apropos of 238 renal excisions with 64 cases of venous invasiveness].

About a series of 238 surgically managed renal cell carcinoma with 64 venous invasion's cases (without no lost of follow-up) the prognosis is bad: post-operative mortality: 12,5%. Overall uncorrected five-years actuarial survival: 25%. But 42% of these patients with venous invasion had associated lymph node invasion and-or visceral metastasis. About 37 cases with only venous extension five-years actuarial survival reaches 45,9%. The inferior vena cava (I.V.C.) extension is the worst. Five american data reports some cases (5 to 18 cases) with near half and half surviving patients. In this series about 14 isolated I.V.C. invasion, only 4 patients are surviving with no evidence of disease but 2 have more than six years and fourteen years follow-up.

Actuarial Analysis↗
PubMed1984

[Is the improvement of survival in advanced bladder cancer possible?].

A retrospective study included 41 cases of bladder cancer, with deep invasion of the muscles (C) or perivesicular cellular tissue (D), but without detectable metastases, treated curatively by total cystectomy. Comparison was made between a first group of 19 patients not treated by cellulolymphadenectomy and another group of 22 patients in whom curettage was performed to remove cells and nodes and who also received 2 concentrated radiations of 7-5 Gy of telecobalt to the bladder during the immediate pre-operative period. Only 10 patients in the latter group were given routine postoperative chemotherapy. Postoperative mortality was unaltered (10,5% in the first group and 9% in the second), but postoperative survival was markedly affected: 10,5% after 5 years in the first group as against 41% in the second. Five-year life expectancy was therefore increased by a factor of 4 in spite of 9 N+ cancers. In the 2nd group of 19 patients operated upon and regularly followed up 3 years and more 7 are alive. True 5 year survival rate in the 2nd group was therefore 35% as against 10% in the first group. Note that 2 of the 9 N+ patients are alive after 3 years. Aggressive therapy in the 2nd group also drastically reduced pelvic recurrence rate, which dropped from 8 (42,1%) in the first group to 1 (4,5%) in the second. In contrast, the major cause of death (7 cases = 31,8%) in the 2nd series was the development of metastases, without evidence of any pelvic recurrence. The effect of routine chemotherapy is being investigated.

Cobalt Radioisotopes↗
PubMed1984

Comparative study of actuarial survival rates in P3 P4 (N+ Mo) transitional cell carcinoma of bladder managed by total cystectomy alone or associated with preoperative radiotherapy and pelvic lymphadenectomy.

In P3 P4 (N+ Mo) bladder cancer patients we conclude the following: 1) The addition of preoperative radiotherapy and meticulous pelvic cellulo-lymphadenectomy to total cystectomy has improved the actuarial survival at five years from 10.5% to 41%. 2) With this protocol, the pelvic recurrence has been reduced from 47.4% to 4.5% and presently the failures are due to undectectable distant metastases.

Actuarial Analysis↗
PubMed1983

[Value of surgery in metastatic cancer of the kidney].

The authors analyse a series of 186 patients with renal cell carcinoma in which 33 patients of Stage IV, with metastases, underwent Nephrectomy and 3 had also operative removal of metastases appearing in early post nephrectomy follow up. The survival periods have been disappointing (none at 5 years). With a review of literature they discuss about the extent of nephrectomy, whether done with purely palliative aim, or along with attempted curative excision simultaneously of the associated metastases. Even if the spontaneous regressions are exceptional and the improvement of survival duration less frequent, metastases are not always a reason not to remove Renal Cell Carcinoma.

Adenocarcinoma↗
PubMed1983

[Can the long-term survival in cancer of the kidney in adults be improved by cellulo-lymphadenectomy?].

Updating their homogeneous series of 172 Renal Cell Carcinomas treated by Nephrectomy with or without Regional Lymphadenectomy, the authors analyse the results from 3 criteria: lymphatic spread, regional spread, and (to account for inaccuracies of exact staging) the overall results. The addition of Regional Lymphadenectomy has improved the anticipated 5 years survival, thus justifying its addition to Radical Nephrectomy when done for curative aims.

Humans↗
PubMed1982

[Cytology in the detection and followup of urothelial tumors. Critical review of 500 cytologic investigations (authors transl)].

500 cytologic studies were performed in patients who underwent urological explorations. Sensitivity is defined as the ability to identify correctly those patients who have tumoral disease of urothelium: urine cytology is ineffective in detecting benign papilloma, but sensitivity is more than 66% in low grade carcinoma and 80% in high grade carcinoma; cytology was able to detect 4/6 transitional cell carcinomas of the upper urinary tract. Specificity, which is defined as the ability to identify correctly those patients who do not have tumoral disease, is extremely high; thus, careful urological examination must be completed when cytology is positive. Urinary cytology is needed in every urological exploration concerned with urinary tract.

Carcinoma, Papillary↗
PubMed1981

[Distal complications of therapeutic arteriovenous fistulae (author's transl)].

Having observed 4 personal cases, the authors review the distal complications of therapeutic arteriovenous fistulaes. Ischaemic complications are of arterial origin and may be severe: strong pain increasing during dialysis, soft tissue trophic disorders and ulcerations, and functional sequelae. Venous stasis disappear without permanent damage. The carpal tunnel syndrome is of uncertain and probably mixed aetiology and can easily be cured by surgical decompression. The use of small calibre, termino-terminal or latero-terminal distal anastomoses should help to prevent these complications.

Aged↗
PubMed1980

[Migration of cement into the bladder after total hip replacement (author's transl)].

The authors report a case of total hip replacement followed by early infection. The prosthesis was removed after several months but despite this a fistula persisted. Four years later, signs of bladder infection appeared. The patient was operated on and a piece of cement was found inside the bladder and removed. The relationship between the infection and the migration of cement into the bladder is discussed. It was recalled that nay intrapelvic protrusion of cement should be avoided in the course of a total hip replacement.

Aged↗
PubMed1980

[Renovascular hypertension in a child, originating in a lower pole aberrant renal vessel dysplastic stenosis (author's transl)].

Renovascular hypertension in a 15-years-old girl, originating in a lower pole aberrant renal artery stenosis by fibromuscular hyperplasia. Microsurgical management by polar artery reimplantation in the renal artery. Unknown evolutivity and diffusion of arterial dysplasias explain the more and more distal repairs reported in literature concerned with renovascular hypertension in infancy and childhood. Nephrectomy and segmental resection are now only done when revascularization is not possible.

Adolescent↗
PubMed1980

[Congenital recto-urethral fistulas in adults. Two cases (author's transl)].

Presentation of two cases of imperforate anus managed in infancy. In first case, at age of 19, surgical closure of recto-urethral fistula associated to excision of a rectal pouch complicated with infected lithiasis and renal damage provides definitive therapy. In second case, recto-urethral fistula was well tolerated for more than 50 years without renal damage. Simple removal of a prostatic lithiasis partially obstructing fistula, provided fair good result. Etiology of these fistulae, well known in pediatric patients, is then discussed. Management must be adapted to complaints and risks.

Adult↗