[Mesenterico-gonadal spontaneous portacaval anastomoses in cirrhosis. Apropos of 3 cases].
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Biomedical subjects
Publications and source records attributed to A Gerard.
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The results of 631 cancers of the stomach treated by gastrectomy between 1970 and 1983 were closely reviewed in six departments of surgery. This review showed that the prognostic factors determined by resectability, extension of the tumor and lymph node involvement are considered to be reliable following the various pre- and postoperative examinations. In addition, it was shown that most of the gastrectomies were performed following conventional procedures and that the widespread lymph node dissections are not applied in a systematic manner. The postoperative mortality is very low (4.4%) for all the gastrectomies and even lower for the radical gastrectomies (3%). The 5 year survival rate for all the gastrectomies is 15%; this rate amounts to 36% for the gastrectomies performed with a curative aim. In the discussion, the adjuvant radiotherapy and chemotherapy are discussed and their timeliness is shown.
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Parenteral administration of a nutritive mixture in a disposable bag prepared in a specialized center reduces the incidence of complications and allows for ambulatory treatment at home. The authors use a nutritive mixture of glucose solutions, amino-acids and lipids in a single bag. Turbidity studies, morphometric evaluation, the macroscopic aspect of the emulsions as well as bacteriological studies have demonstrated the stability of the solution for 5 days when kept at 4 degrees C. Forty-nine cancer patients benefited by this therapeutic modality. Four patients developed an infection in conjunction with the advent of temporary personnel in specialized unit. One patient developed cholestatic jaundice. All 5 recovered. No other patient suffered from a complication due to this technic of parenteral nutrition. One patient has been treated for 3 months of which 1 month at home. Another one is still on total parenteral nutrition 9 months later with 8 months at home without any complication.
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Between 1968 and 1972, 33 patients with carcinoma of the colon or the rectum underwent a radical surgical procedure followed by adjuvant irradiation therapy. One month after surgery, 6,000 rads were delivered in 6 to 7 weeks. Five of these patients presented later a radiotherapy ileitis, colitis or rectitis. One of them developed a rectitis of the anastomotic area with important diarrheas treated by drugs only; a second presented bowel subobstructions induced by a radiotherapy ileitis and died in cachexy a few months later. The 3 other patients underwent surgery again; one of them for adhesions in the anastomotic area: a definite left colostomy was realized for a stenosic rectitis in the second patient; the last patient underwent surgery 4 times again and died from a rupture of the iliaca artery. Discussion on the observations made at surgery and on the surgical pathology data could explain the high rate of these iatrogenic lesions induced by radiotherapy.