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Biomedical subjects

A Gentili

Publications and source records attributed to A Gentili.

At least 73 records · Page 4Linked to original sources

Nonosseous accumulation of bone-seeking radiopharmaceuticals.

Bone scintigrams are usually obtained for evaluation of skeletal abnormalities; soft-tissue abnormalities are often an unexpected finding. However, the recognition of specific conditions with extraskeletal accumulation of bone-seeking radiopharmaceuticals greatly enhances the diagnostic value of the study. Several examples of abnormal nonosseous uptake in both neoplastic and nonneoplastic processes involving the brain, lung, heart, breast, bowel, liver, spleen, skeletal muscle, kidney, and bladder are presented. Examples of artifactual uptake in the soft tissues are also described. Causes for nonosseous accumulation are discussed.

Bone and Bones↗

MR imaging of the postoperative lumbar spine: assessment with gadopentetate dimeglumine.

This study defines the accuracy of gadopentetate-dimeglumine-enhanced MR imaging in patients with failed back surgery syndrome by comparing the imaging studies with surgical findings in a large patient population. From June 1988 to March 1989, 193 postoperative patients had MR imaging of the lumbar spine both with and without contrast administration. Of this group, 27 had repeat surgery at 31 levels: these patients comprise the study group. Postcontrast MR diagnoses were as follows: scar only (n = 4), disk only (n = 13), scar and disk (n = 9), and no aberrant epidural tissue (n = 5). Surgical diagnoses differed from the MR diagnoses in two patients at two levels. In one patient, disk was diagnosed on MR while osteophyte was present at surgery. In the other patient, scar only was diagnosed by MR but disk and scar were present at surgery. These data, when combined with the authors' previous experience, give pre- and postcontrast MR a 96% accuracy in differentiating scar from disk in 44 patients at 50 reoperated levels. For patients 6 or more weeks past surgery, sagittal and axial T1-weighted MR imaging before and after administration of gadopentetate dimeglumine is an effective method of evaluating the postoperative lumbar spine.

Adult↗

[Acute intermittent porphyria: a clinical case].

The acute intermittent porphyria is a rare but very interesting disease from the surgical and anaesthesiological point of view. On the basis of recently observed case the Authors review clinical and pathophysiological data of this entity simulating a variety of acute abdominal conditions and involving important problems from the anaesthesiological and pharmacological point of view. As a matter of fact, the administration of some drugs can provoke a crisis that often involves serious complications (coma), sometimes lethal (respiratory paralysis). However, when a patient needs a surgical treatment for different reasons, the awareness of this condition enables to plan an anaesthesiological management free of risks.

Abdomen, Acute↗

Prevention of deep venous thrombosis in patients with acute spinal cord injuries: use of rotating treatment tables.

A randomized clinical trial of 15 patients with acute spinal cord injuries was performed to test the hypothesis that rotating treatment tables prevent deep venous thrombosis in this population. Four of 5 control (nonrotated) patients developed distal and proximal thrombi, assessed by 125I fibrinogen leg scans and impedance plethysmography. In comparison, only 1 of 10 treated (rotated) patients developed both distal and proximal thrombosis (P = 0.007). These results suggest but do not prove that rotating treatment tables prevent the development of proximal deep venous thrombosis in spinal cord-injured patients. Larger clinical trials are needed to confirm this heretofore undocumented benefit of rotating treatment tables.

Beds↗

60Co in air.

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Air Pollution, Radioactive↗