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Biomedical subjects

A Gauthier

Publications and source records attributed to A Gauthier.

At least 127 records · Page 7Linked to original sources

[Ultrasonic exploration of porto-caval shunts (author's transl)].

Ultrasonography was used to explore surgical porto-caval shunt in 10 patients. In 9 of these, the patency demonstrated by angiography was confirmed, the communication between the two veins being clearly visible on 9 transverse sections, 6 sagittal sections and 2 right frontal sections. In addition, the echograms supplied information on the size of the opening, the calibre of the inferior vena cava (which was usually dilated below the anastomosis) and, in some cases, the presence of thrombosis. Harmless and readily accepted by the patients, ultrasonography is likely to become one of the preferred methods for post-operative control of porto-caval shunts.

Angiography↗

The action of anti-inflammatory drugs on the fertility of female rats with intrauterine contraceptive devices.

A silk thread (0-0) or a copper wire (0.18 mm diameter) was placed in the left uterine horn of rats, at least 3 days before fertilization. The animals were untreated or given daily injections of 3 mgh hydrocortisone or 30 mg aspirin beginning the day after insertion of the IUD; 2 weeks after coitus, the animals were killed. A longitudinal (less than or equal to 10 mm) silk thread and the copper wire were effective IUDs regardless of treatment. With the short silk thread (less than or equal to 2 mm), implantation occurred in all groups of rats but a high failure rate was observed in hydrocortisone-treated rats (5/9 with implantations). The no. of implantations/no. of corpora lutea (x 100) was much higher (20.4%) in rats treated with aspirin and hydrocortisone than in untreated animals (3.2%) (P less than 0.01). We conclude that the effectiveness of an IUD can be altered by treatment with an anti-inflammatory substance.

Animals↗

New therapeutic approach to corrosive burns of the upper gastrointestinal tract.

The therapeutic approach to the management of corrosive burns of the upper gastrointestinal tract leaves a considerable morbidity and a heavy mortality rate. This work evaluates the effectiveness of a new therapeutic approach given to 94 consecutive patients. The management has been based on three major points: (1) the definition of extent of upper gastrointestinal lesions by immediate fibroendoscopy; (2) immediate protection of the upper gastrointestinal tract by total parenteral nutrition in cases with serious burns (41 cases), normal oral nutrition being allowed for minor burns (35 cases); (3) reparative surgical procedures for any of the sequelae of such burns during the fibrosing phase. The results were as follows: (a) healing, depending upon the degree of burn, occurred between eight to 90 days; (b) the frequency of subsequent local complications was small with total parenteral nutrition started a few hours after ingestion of the corrosive product; (c) after reconstructive surgery no serious complications occurred; (d) the overall morbidity stayed at a very low level (four patients). We conclude that the general prognosis of a severe burn of the upper gastrointestinal tract, without other trauma, is appreciably improved by the very early institution of total parenteral nutrition.

Adolescent↗

[Significance and characteristics of enteral nutrition in massive intestinal resections].

There is an increasing number of patients who have lad massive resection of the small intestine, and they pose a problem of how to readapt their nutrition. This has to take into account their malabsorption syndrome due to the extent and site of the resection. Other factors which may affect their nutritional status are whether the caecum has been left in place, the functional capacity of the remaining small intestine and the hepatic and pancreatic functions. This process of readaptation is luckily helped by the compensating hyperplasia of the remaining small intestine especially clearcut in the ileum. This organ and this process is closely related to the presence of food and biliary pancreatic secretions in the intestinal lumen. This is a strong argument in favour of early oral feeding of these patients. It should start two to three weeks after the operation with at the same time intravenous feeding being continued until such time as the intestine can adequately take over. Nevertheless at the beginning simple food is used, which can be absorbed directly (glucose, amino acids, medium chain triglycerides--MCT). These are given slowly and continuously by a silicon nasogastric tube. After some time when the patient has become used to this, he can be fed orally to a slightly greater extent, with the food divided into five or six meals.

Adaptation, Physiological↗

[A preliminary study of the components causing poor utilization of barley in the young chicken].

The effect of barley on the characteristics of the intestinal contents and on the growth performance has been studied in the young chicken (5 to 27 days) by comparing 5 different varieties of barley: 2 six-rowed winter barleys (Astrix and Sympa)), 2 two-rowed winter barleys (Alpha and Sonja) and 1 two-rowed spring barley (Aramir). All the barleys were used in the ration at a rate of 50 p. 100 to constitute 5 complete, balanced diets which were similar (e.g. energetic value, amino acids) to each other and to a control diet of corn and soya. There was no relation between the characteristics (in particular, viscosity of barley soluble components) of the barleys studied in this trial and the growth performances obtained. On the other hand, the 2 barleys (Astrix and Alpha) which caused retarded growth and a significant increase in the conversion rate were the same ones modifying the viscosity of the intestinal contents. The barley intolerance of the young chicken is thus related to the presence of undigestible, viscous components which are difficult to determine by a simple water extraction of the barley.

Aging↗

[Acute pituitary failure as the presentation of a prolactin cell adenoma during a pregnancy made possible by bromocriptine (author's transl)].

A 21-year-old woman had sterility due to amenorrhoea-galactorrhoea with hyperprolactinaemia and hypoplastic ovaries. The sella turcica was asymmetrical but tomograms were suggestive of a congenital appearance. There was no suprasellar expansion. Treatment with bromocriptine and HMG resulted in pregnancy. Acute pituitary failure occurred at the 10th week, revealing an adenoma. The pregnancy proceeded to term after hypophysectomy. This complication, the first reported under the effects of bromocriptine, may serve as a reminder of the precautions to be taken during pregnancy in a hyperprolactinaemic woman.

Adenoma↗