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Biomedical subjects

A Gatti

Publications and source records attributed to A Gatti.

101 records · Page 6Linked to original sources
PubMedDate not supplied

[Effect of male and female hormones on the appearance and development of experimental 20-methylcholanthrene-induced tumors in young albino rats].

A review of the relevant literature is followed by an investigation of the effect of male and female hormones on the onset and growth of 20-methylcholanthrene induced tumours in approximately 15-day-old rats. The results indicated that oestrogens facilitate the onset of tumours in females, and hinder it in males, whereas testosterone provokes tumours in both males and females, contrary to what happens in the adult rat. It is felt that the latter finding can be ascribed to the fact that, since the transformation of oestradiol from testosterone usually takes place at 12 months (Di Prisco et al)., the antagonist effect between hormones of different sex which appears to oppose tumour growth had not yet occurred. This, then could be one of the reasons for carcinogenesis in female rats treated with testosterone, aided by hormonal stimulus of cell glycolysis.

Age Factors↗
PubMedDate not supplied

[Portacaval anastomosis with a bypass of lyophilized dura mater. Experimental research in young dogs].

A review of the relevant literature is followed by an account of the use of freeze-dried dura mater prostheses in the construction of porta-cava anastomoses in young dogs. Results of an experiment showed that involution of the dura mater in the new passage between the porta and the cava was followed by the establishment of connective tissue only, and later by the appearance of smooth muscle. The conclusion is drawn that this material gives satisfactory results and is ripe for further development, using various modalities.

Animals↗
PubMedDate not supplied

Isolation of an adenovirus from an ostrich (Struthio camelus) causing pancreatitis in experimentally infected guinea fowl (Numida meleagris).

An adenovirus was isolated from the pancreas, kidney, and lung of a dead 4-month-old ostrich (Struthio camelus). Experimental infection of week-old guinea fowl (Numida meleagris) was carried out in order to study transmission. Of the infected keets, six out of 15 died; these exhibited pancreatitis, presence of a hemorrhagic liquid in the abdominal cavity, kidney degeneration, and pulmonary lesions. The remaining birds, euthanatized on day 21 postinoculation, showed chronic pancreatitis. The virus was reisolated from the pancreas, lung, and kidney of the infected keets.

Adenoviridae Infections↗
PubMedDate not supplied

[Distribution of blood lead level in a general population].

The goal of this study was to evaluate the distribution of blood lead level (B.L.L.) in a general adult population aged between 20 and 79 years non professionally exposed to lead, and to verify the influence on B.L.L. of demographic variables (i.e. sex and age), behavioural habits (i.e. alcohol consumption and cigarette smoking), and anthropometric variables (i.e. body mass index--BMI). We studied the distribution of B.L.L. by explorative analysis method (E.D.A.), which showed that data did not follow a Gaussian distribution. Distribution fit to normality was determined by Shapiro-Wilk test, that identified the natural logarithm of B.L.L. as the best transformation in order to normalize the parameter. According to literature data, sex appears one of the most important variable in determining B.L.L. In both sexes we found a direct relation between B.L.L. and age. Alcohol consumption emerged as the third most important variable that influences B.L.L. BMI and cigarette smoking do not influence data distribution.

Adult↗