Colchicine therapy in recurrent oral ulcers.
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Adult↗
Biomedical subjects
A Gatot
Publications and source records attributed to A Gatot.
Branchial cleft cyst manifesting as hypoglossal nerve palsy.
Hypoglossal nerve palsy occurred in 2 patients with infected second branchial arch cleft cyst. This very unusual complication of the congenital anomaly has been related to the mechanical compression of the mass. Histologic features of the perineural coat were also suggestive for this etio-pathogenesis.
Adult↗
T-tube modification to decrease the risk of plugging.
Laryngotracheal stenosis is a recognized complication of local injuries, such as prolonged intubation. Surgical reconstruction with the use of a tracheal T-tube is widely recommended. We report a serious complication consisting of the sudden obstruction of the T-tube by viscous secretions. In order to prevent this undesirable consequence, a simple modification of the T-tube technique is proposed.
Airway Obstruction↗
Temporomandibular arthritis in familial Mediterranean fever.
Temporomandibular joint arthritis is a rare manifestation of familial Mediterranean fever and should be considered in patients of Mediterranean origin. Recently we treated four patients suffering from this condition, and intra-articular corticosteroid injection resulted in rapid resolution of the pain and disability in two. Computed tomography confirmed the usefulness of this therapeutic modality.
Adult↗
Nasal histamine challenge: a method to predict the efficiency of antihistamine treatment.
Nasal histamine challenge (NHC) was performed on patients suffering from chronic rhinitis. The histamine was administered to the nose in the form of a spray. One hundred sixty-eight patients and 20 healthy subjects were examined. The histamine was sprayed into the nose in seven metered doses, from 0.03 mg to 3 mg. The nose was examined before and 4 minutes after each challenge. A positive reaction to challenge was indicated when the conchae swelled to the point that they impinged against the septum. We found that some patients reacted to a low dose of histamine (0.03 mg to 0.15 mg) while our control group and some other patients reacted positively only to higher doses of histamine (3 mg or more). After the first tests, NHC patients were randomly divided into two groups. One group was treated with placebo and the other group with antihistamines. Three weeks later another NHC was performed (now under treatment) and revealed that patients reacting to low doses of histamine improved significantly with antihistamine treatment, while those reacting to a high dose did not respond to antihistamines. We found the NHC to be a simple test with no complications, and one that is easily tolerated by patients, including children. Nasal histamine challenge helps to identify which patients will improve with antihistamine treatment and aids the evaluation of its efficacy.
Adolescent↗