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Biomedical subjects

A Gamba

Publications and source records attributed to A Gamba.

77 records · Page 5Linked to original sources
PubMedDate not supplied

[Smoking cessation course organized by the Italian League for the fight against tumors in Milan and Rome: determinants of cessation after the course and after a year].

The Italian League against Cancer organizes a group behaviour therapy program for smoking cessation in Milan and Rome. Groups meet for 8-9 sessions; sessions are managed by a therapist. In the analized courses participants are 43-44 years on the average, with a middle/high level of education. They are heavy smokers with a high level of nicotine dependence and they greatly trust in the program. At the end of the program 67% of participants in Milan and 76% in Rome declare they no longer smoke. One year later, phone interviews show that 22% of participants in Milan and 25% in Rome are still non smokers. At the end of the program quitting-smoking predictors are: attendance at at least 6-7 sessions, smoking less than 30 cigarettes a day before the course and male gender; one year later attendance at at least 6-7 sessions, and scarce nicotine dependence (smoking less than 30 cigarettes a day before the program or a low score at the Fagerström Tolerance Questionnaire).

Adult↗
PubMedDate not supplied

[Efficacy and difficulty in a program of home care for patients with cancer in an advanced stage].

The difficulties experienced by nurses working in a service for domiciliary assistance have been studied through a series of three observations performed at the occasion of the weekly team meetings, at the first visit, the second week of treatment, the week preceding interruption of therapy. Pain problems pose far less difficulties than those linked to the overall physical and psychological management of the patients, which worsen as the time goes on. Specific attention is given to the familiar setting and to the motives which lead to the interruption of the nursing relationships.

Communication↗
PubMedDate not supplied

ESR investigation of the structural transition of spectrin in ghosts and in solution.

The effect of temperature on the human erythrocyte ghosts and on isolated spectrin, both labelled with a protein spin label (2, 2, 6, 6 tetramethylpiperidin - 1 - oxyl - 4 - maleimide), was studied by the electron spin resonance spin label method. The results show that the spectra associated with the membrane undergo significant changes with temperature and a well-defined transition is detected at 52 degrees C. The observed transition is removed from the membrane by the extraction of spectrin and in the supernatant the transition is unchanged from that exhibited by the native ghosts. The results show that it is possible to observe the heat dependent transition of the spectrin in whole ghosts avoiding the extraction procedure.

Electron Spin Resonance Spectroscopy↗
PubMedDate not supplied

Pediatric heart transplantation without chronic maintenance steroids.

From 1986 to February 1993, 40 children aged 2 months to 18 years (average age 10.4 +/- 5.8 years) underwent heart transplantation. Indications for transplantation were idiopathic cardiomyopathy (52%), congenital heart disease (35%) with and without prior repair (71% and 29%, respectively), hypertrophic cardiomyopathy (5%), valvular heart disease (3%), and doxorubicin cardiomyopathy (5%). Patients were managed with cyclosporine and azathioprine. No prophylaxis with antilymphocyte globulin was used. Steroids were given to 39% of patients for refractory rejection, but weaning was always attempted and generally successful (64%). Five patients (14%) received maintenance steroids. Four patients died in the perioperative period and one died 4 months later. There have been no deaths related to rejection or infection. Average follow-up was 36 +/- 19 months (range 1 to 65 months). Cumulative survival is 88% at 5 years. In patients less than 7 years of age, rejection was monitored noninvasively. In the first postoperative month, 89% of patients were treated for rejection. Freedom from serious infections was 83% at 1 month and 65% at 1 year. Cytomegalovirus infections were treated successfully with ganciclovir in 11 patients. No impairment of growth was observed in children who underwent transplantation compared with a control population. Twenty-one patients (60%) have undergone annual catheterizations and no sign of graft atherosclerosis has been observed. Seizures occurred in five patients (14%) and hypertension was treated in 10 patients (28%). No patient was disabled and no lymphoproliferative disorder was observed.(ABSTRACT TRUNCATED AT 250 WORDS)

Adolescent↗