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Biomedical subjects

A Galloway

Publications and source records attributed to A Galloway.

67 records · Page 4Linked to original sources
PubMed1987

An outbreak of Salmonella typhimurium gastroenteritis in a psychiatric hospital.

An outbreak of Salmonella typhimurium (phage type 12) infection involving 11 patients and 12 members of staff occurred in a psychiatric hospital in Merseyside during a 3-week period in September and October 1984. Bacteraemia did not occur in any patients, those affected having a mild self-limiting diarrhoea. The source of the organism remained unknown but the most probable means of transmission was by person to person contact. The outbreak was controlled by transferring affected patients to an isolation ward. Staff were encouraged to report gastrointestinal symptoms and remain off work until symptom free or until the results of cultures were known. The problems of managing the outbreak are discussed.

Cross Infection↗
PubMed1986

Haemochromatosis presenting with a double Yersinia infection.

A patient suffering from diabetes mellitus presented with Yersinia pseudotuberculosis septicaemia and serological evidence of concomitant infection with Yersinia enterocolitica. He was later shown to have idiopathic haemochromatosis.

Antibodies, Bacterial↗
PubMed1986

Serial concentrations of C-reactive protein as an indicator of urinary tract infection in patients with spinal injury.

C-reactive protein (CRP) was measured serially in 16 patients with an acute spinal injury. Twelve episodes of acute urinary tract infection (UTI) occurred during the study period. These were all associated with an increased concentration of CRP greater than 50 mg/l, which returned to normal after successful treatment. Thirteen episodes of asymptomatic bacteriuria associated with increased concentrations of CRP greater than 20 mg/l occurred, indicating tissue damage. More commonly, significant bacteriuria was associated with normal concentrations of CRP, and presumably, simple colonisation of the urinary tract, which, we suggest, does not require treatment with antibiotics. Serial measurement of CRP in patients with spinal injury may help distinguish between urinary tract colonisation and infection and be useful in monitoring the response to the treatment of clinical UTI.

Acute Kidney Injury↗
PubMed1985

A new synthetic inhibitor of mammalian tissue collagenase inhibits bone resorption in culture.

A specific and potent synthetic inhibitor of mammalian tissue collagenase and related metallo-proteinases inhibits the collagen matrix resorption induced by parathyroid hormone (PTH) in cultured embryonic mouse calvaria. The inhibition is reversible, dose-dependent and virtually complete at 50 microM inhibitor concentration whereas that due to a less potent stereoisomer is much weaker. The PTH-enhanced secretion of calvarial lysosomal enzymes and the small spontaneous leakage of lactate dehydrogenase are not affected by the inhibitor. These results suggest that collagenase plays a critical role in bone resorption. Its role is discussed in relation to that of cysteine-proteinases that have also been implicated in this process.

Animals↗
PubMedDate not supplied

Atypical presentation of dissection of the ascending aorta in young men with cystic medial necrosis: MR findings.

Dissection of the ascending aorta is usually associated with severe chest and/or back pain. We describe three young men, with pathologically proven cystic medial necrosis, who presented with atypical clinical symptoms and ascending aortic dissection diagnosed by MR imaging and surgery. Patients with cystic medial necrosis and aortic dissection may not present with a classic acute chest pain syndrome.

Adult↗
PubMedDate not supplied

Fine needle aspiration cytology of an ectopic parathyroid adenoma: a case report.

BACKGROUND: Surgical exploration in the region of the neck identifies a majority of parathyroid adenomas; however, in individuals in whom surgical exploration has failed, fine needle aspiration (FNA) biopsy can be useful. Ectopic parathyroid adenomas can be rapidly diagnosed by the cytologic appearance of aspirate smears with the identification of stromal and intracellular lipid on oil red O-stained smears. CASE: A 59-year-old male presented with hyperparathyroidism; surgical exploration of the neck in the region of the thyroid gland failed to identify any parathyroid abnormality. Subsequent imaging with (99m)technetium and (201)thallium showed a mass in the left supraclavicular region that, on FNA biopsy, was confirmed as an ectopic adenoma. Removal of the adenoma resulted in normal serum calcium levels. CONCLUSION: FNA can be successfully utilized in the localization of ectopic parathyroid tissue.

Adenoma↗