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Biomedical subjects

A G Khomasuridze

Publications and source records attributed to A G Khomasuridze.

At least 19 recordsLinked to original sources
PubMed2006

[Antiprogesterone for medical abortion].

The purpose of the research was to evaluate clinical course and efficiency of the method of termination of pregnancy in the first end second trimesters by means of antiprogesterone. 384 women aged 15 to 45 in the first end second trimesters of pregnancy were investigated. 300 women had an early pregnancy (range=2-7 weeks) requesting abortion. All these women first took 600 mg antiprogesterone pencroftone ("Pencroft-Fharma", Russia) and 48 hours later - 400 mkg prostaglandin misoprostol. 84 patients with gestation period ranged from 14 to 22 weeks. Their contractility utterly was caused with 400 mg pencroftone and 48 hours later with 400 mkg prostaglandin misopristol. In the first trimester completed abortion was observed in 96,7%, incomplete abortion in 1,7%; missed abortion in 2,3% cases, continuing pregnancy in 1 case. In the second trimester in the case of therapy with pencroftone and prostaglandin E1 misoprostol the clinical effect was observed in 96,4% cases. Antiprogesterone pencroftone is an effective for medical abortion during I-II trimesters of pregnancy. It is characterized by minimal risk of complications in the course and the post abortion period.

Abortifacient Agents, Steroidal↗
PubMed1993

[The characteristics of hormonal contraception in women with hyperandrogenism].

One hundred and ten fertile women with such androgenism signs as seborrhea, acne, and hirsutism were examined to elucidate the contraceptive and therapeutic efficacy of hormonal contraceptive drugs anteovin, marvelon, and diane-35. The duration of pill administration for each women depended on her cycle duration. All the drugs had a 100% contraceptive efficacy and exerted a therapeutic effect on androgenism symptoms.

Acne Vulgaris↗
PubMed1977

[Effect of oral contraceptives on the blood lipid level].

Secretion of estrogens in the urine and the content of cholesterol and triglycerides in blood plasma were studied in 36 healthy women 24 of whom took oral contraceptives including estrogenic and gestagenic components to prevent conception. It proved that after the first course of medication the overall estrogen excretion reduces at the expense of all fractions but more so at the expense of the active fraction. Beginning with the 2nd week the cholesterol level in the blood plasma increases and the level of triglycerides grows considerably. The increase in these indices was observed in the first 6 months when the oral contraceptives were taken. With the preparations taken for a longer time the blood plasma cholesterol and triglyceride levels became stable.

Adult↗