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Biomedical subjects

A G Canavan

Publications and source records attributed to A G Canavan.

24 records · Page 2Linked to original sources
PubMed1989

Classical conditioning in patients with severe memory problems.

Classical conditioning is one of the most fundamental forms of learning, and yet little is known regarding the effects of brain injury on conditioning processes in humans. Three patients with temporal lobe lesions and severe memory problems were therefore assessed in terms of eyeblink conditioning, extinction, discrimination and reversal learning, and in one patient electrodermal conditioning was also investigated. The acquisition of conditioned responses was seen to be intact, but the evidence regarding extinction was ambiguous. All of the patients were impaired in discrimination learning and also reversal learning.

Adult↗
PubMed1988

Verbal and abstract designs paired associate learning after unilateral temporal lobectomy.

The combined use of a new abstract designs Paired Associates test with the Verbal Paired Associates test of Form 1 of the Wechsler Memory Scale was investigated with respect to eliciting material specific memory deficits after unilateral temporal lobectomy. Although the verbal test differentiated between the memory ability of these two groups more clearly than the abstract designs test, the effectiveness of looking at the difference between total scores on the two tests was demonstrated. The two tests produced similar levels of performance in control subjects.

Analysis of Variance↗
PubMed1987

Lateralisation of memory functions in epileptic patients by use of the sodium amytal (Wada) technique.

Lateralisation of speech and memory functions was determined in 27 patients, being assessed for surgical treatment of unilateral temporal lobe epilepsy, using the sodium amytal procedure. The most common outcome with regard to language was the retention of normal left hemisphere dominance, regardless of handedness or side of lesion. In contrast, memory functions were most often to be found only in the unaffected hemisphere, also regardless of handedness or side of lesion. A lesion of either hemisphere appeared capable of interfering with language and verbal memory functions in an unexpectedly high proportion of patients.

Adolescent↗
PubMed1985

Luria's frontal lobe syndrome: psychological and anatomical considerations.

Luria has described a syndrome of disinhibited and impulsive behaviour, in which the patient is unable to follow sequential instructions. This he attributes to localised frontal lobe damage. However, group studies of patients with focal lesions of the frontal lobes fail to reveal such a syndrome. A patient is described who displayed a form of Luria's syndrome temporarily. Psychometric and post mortem evidence indicate that the syndrome arises only under conditions of more global cerebral dysfunction.

Brain↗
PubMed1983

Stylus-maze performance in patients with frontal-lobe lesions: effects of signal valency and relationship to verbal and spatial abilities.

In 1964-1965 Milner demonstrated that patients with frontal lobe lesions display deficits on a stylus-maze task, and suggested that this is due to a dysfunction of the ability to change responses-set readily in accordance with varying environmental signals. Patients with frontal lobe lesions were tested on either the traditional form of the task (which emphasizes errors), or on a form which emphasizes correctness. Both groups displayed deficits, but there were no significant differences between groups. Errors were negatively correlated with spatial IQ, while rule-breakages were negatively correlated with verbal IQ.

Adolescent↗