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Biomedical subjects

A Fraser

Publications and source records attributed to A Fraser.

At least 127 records · Page 7Linked to original sources
PubMed1984

Cortisol suppression index in major depressive illness.

This study compares the utility of a cortisol suppression index with the standard dexamethasone suppression test as a diagnostic aid for major depressive disorder. In 50 patients the cortisol suppression index was found to have similar sensitivity while also having greater specificity and diagnostic confidence than the dexamethasone suppression test. By avoiding the need for a late-evening blood sample, the cortisol suppression index may be an acceptable alternative to the current procedure.

Bipolar Disorder↗
PubMed1982

The filling-in illusion and moving visual phantoms.

A new visual illusion, filling-in illusion, is reported and compared to the moving visual phantoms of Tynan and Sekuler (1975). 169 unrelated, unpaid, volunteer subjects were recruited from students and faculty and classified as filling-in positive--able to perceive the illusion, or filling-in negative--unable to perceive it. Other investigations examined the effects of light levels, moving vs static test figures, and black-and-white vs shaded figures. A polaroid study suggests a central rather than retinal location of the illusory effect. Filling-in is a contour completion effect, as are moving visual phantoms. Although a number of differences between the two phenomena exist, it is suggested that they may be due to different aspects of a common mechanism.

Fixation, Ocular↗
PubMed1980

Microscopy.

Explore the source record for details and available documents.

Candidiasis, Vulvovaginal↗
PubMed1979

Perception of illusory movement.

Intensive studies of visual illusion have rarely shown examples of polymorphic responses. We show here that, using figures consisting of stripes shaded from dark to light, arranged in repeating sectors, an illusion of movement can be induced in about 75% of observers when viewed peripherally. The responses of the viewers fall into four categories. This polymorphic response suggests a genetic origin.

Female↗
PubMed1979

The use of antibiotics in general practice.

The prescribing of antibiotics in extra-hospital practice has now reached a level of one sixth of all Australian Pharmaceutical Benefit scheme prescriptions. In the last documented year prescriptions for the penicillins alone amounted to almost eight millions. Is this wholesale prescribing of potent, expensive, and, at times, dangerous chemotherapy really justified. This article will examine the indications for overall use of antibiotics, the pitfalls of their careless prescribing, and briefly review the main indications for each group of drugs in regular use in family practice. The discussion will therefore not include some drugs which are ordinarily limited to hospital practice, nor many of the regimes used in serious or life threatening disease such as meningitis or septicaemia.

Anti-Bacterial Agents↗
PubMed1976

Polymorphism in a cyclic parthenogenetic species: Simocephalus serrulatus.

A survey of sixteen isozyme loci using electrophoretic techniques was conducted for three isolated natural populations and one laboratory population of the cyclic parthenogenetic species, Simocephalus serrulatus. The proportion of polymorphic loci (33%-60%) and the average number of heterozygous loci per individual (6%-23%) in the three natural populations were found to be comparable to those found in most sexually reproducing organisms. Detailed analyses were made for one of these populations using five polymorphic loci. The results indicated that (1) seasonal changes in genotypic frequencies took place, (2) apomicitic parthenogenesis does not lead to genetic homogeneity, and (3) marked gametic disequilibrium at these five loci was present in the population, indicating that selection acted on coadapted groups of genes.

Alkaline Phosphatase↗