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Biomedical subjects

A Fournie

Publications and source records attributed to A Fournie.

At least 37 records · Page 2Linked to original sources
PubMed1990

[Hip algodystrophy and pregnancy].

We report two cases of algodystrophy of the hip in pregnancy. The principle characteristics of the condition are: the occurrence of the symptoms in the second or third trimester of the pregnancy; and these are more marked on the left than on the right hip and radiological decalcification. MRI is accurate, specific and non invasive and it has largely taken the place of scintigraphy and tomodensitometry in making the diagnosis and in the differential diagnosis of early aseptic necrosis of the femoral head. Recovery always occurs in less than a year without sequelae. The physiopathogenic mechanism still is to be discussed but it does seem that the mechanical factors play a very important role.

Adult↗
PubMed1989

Thyroid plasmacytoma with dermatomyositis and palmar fasciitis.

A 74-year-old woman with a primary thyroid plasmacytoma was studied. Clinical signs included a mass in the neck, as well as muscle and skin involvement due to dermatomyositis. In her serum a monoclonal IgG lambda was present. Immunohistochemistry showed an intracellular monoclonal IgG lambda component. After thyroid surgery and radiation, clinical improvement and fall of M protein were noted. On longterm followup, only palmar fasciitis persisted.

Aged↗
PubMed1989

[Desmoid tumors of the anterior abdominal wall. Apropos of a case].

The authors describe a case of a desmoid tumor of the anterior abdominal wall. From a review of the world literature, the main characteristics of these tumors are detailed, and the various pathophysiological hypotheses, demonstrating the necessity of exclusively surgical treatment, are presented.

Abdominal Muscles↗
PubMed1988

The transsynovial lymphocytic ratio. Characterization of blood and synovial fluid lymphocytes from patients with arthritic diseases.

Monoclonal antibodies and flow cytometry techniques were used to analyze and compare the distribution of lymphocyte subpopulations of peripheral blood and synovial fluid (SF) from 70 patients, 43 with rheumatoid arthritis (RA), 10 with ankylosing spondylitis (AS) or reactive synovitis, 10 with psoriatic arthritis and 7 with other inflammatory arthritic diseases. Patients with RA had significantly reduced number of CD8+ T cells and greater CD4/CD8 ratios in peripheral blood, a greater number of CD4+ T cells and lower CD4/CD8 ratio in SF. No significant difference was found between the groups with AS, reactive synovitis and psoriatic arthritis. The simultaneous analysis of peripheral blood and SF lymphocyte subpopulations allowed us to establish a transsynovial lymphocytic ratio which reflects CD4/CD8 variations on both peripheral blood and SF, 2 easily accessible compartments for physicians. This new ratio may distinguish RA from other inflammatory arthritic diseases.

Arthritis↗
PubMed1987

[Fetal blood sampling under ultrasonic control].

Withdrawing foetal blood from the umbilical cord under ultrasonic control requires close co-ordination between obstetricians and echographists. The most important indications for this procedure are infections and foetal karyotype determination.

Blood Specimen Collection↗
PubMed1985

IgG subclasses and Gm allotypes of anti-D antibodies during pregnancy: correlation with the gravity of the fetal disease.

The IgG subclasses and the Gm allotypes of anti-D antibodies were studied in 103 isoimmunized pregnancies with Rh-positive infants. No allelic exclusion phenomena were observed in patients heterozygous for the studied genes. An analysis of the correlation between the severity of fetal disease and the type of anti-D antibodies shows a greater hemolytic action of the IgG1 subclass and, within this group, those marked by the Gm(4) allotype. These results suggest that the prognostic value of anti-D antibody titers during pregnancy could be modulated by a study of the IgG subclasses and their allotypes.

Bilirubin↗
PubMed1983

[Double-blind comparative study of Bi-Profenid tablets and Profenid capsules in inflammatory rheumatism].

The effectiveness of Bi-Profenid tablets and Profenid capsules was studied comparatively in patients with inflammatory joint disease. 43 patients with rheumatoid arthritis or various chronic inflammatory joint diseases were given 300 mg of Bi-Profenid in 2 daily oral doses and 300 mg of Profenid in 3 daily oral doses, for two consecutive 7 day periods. This double blind cross-over study was carried out in two rheumatology centers. Effectiveness of the two forms of ketoprofen on morning stiffness and pain scale was found to be comparable. However, patients more often preferred Bi-Profenid (15 cases) to Profenid (10 cases); 12 patients reported no difference. Tolerance was excellent in 92.7% of cases under Profenid capsules and in 94.8% of cases under Bi-Profenid tablets.

Adolescent↗
PubMed1982

[Pirprofen in the treatment of rheumatoid arthritis].

The efficacy and tolerance of pirprofen and ketoprofen in rheumatoid arthritis were compared in a cooperative, double-blind, cross-over trial involving 124 patients. Pirprofen 600 mg/day and ketoprofen 300 mg/day were given one after the other in a random order for two consecutive weeks. One hundred and ten patients were evaluated. Both drugs were comparable in efficacy, as evaluated on 12 different clinical and biological criteria with a tendency toward superiority for pirprofen. Pirprofen was very well tolerated by 79% and ketoprofen by 72% of the patients. Most of the side effects encountered were digestive disorders. In patients who received no other concomitant treatment, pirprofen was better tolerated than ketoprofen. Side effects were noted in only 9% of the patients under pirprofen, as against 25% under ketoprofen.

Adult↗
PubMed1982

Cytochemical profile of peripheric blood lymphocytes in 7 to 27 weeks' pregnancy.

A comparative study of alpha-naphthyl (nonspecific) esterase (ANAE), acid phosphatase (AcP), and beta-glucuronidase (beta-GLUS) in the blood lymphocytes was carried out on 26 healthy pregnant women (7 to 27 weeks' amenorrhea) and on 32 normal nonpregnant women, all 58 of whom were 19 to 34 years old. In pregnant women, we found a significantly lower percentage of ANAE-positive lymphocytes (after 11 weeks' amenorrhea), a strong reduction in AcP, and a slight decrease in beta-GLUS. The modified enzyme levels of circulating lymphocytes in the early stages of pregnancy seem to be related to the depressed cell-mediated immunity.

Acid Phosphatase↗