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Biomedical subjects

A Foster

Publications and source records attributed to A Foster.

216 records · Page 12Linked to original sources

New treatments in ulcer healing and wound infection.

This review examines several of the recently introduced wound care products that have been put forward as treatment modalities for the diabetic foot ulcer. Discussed are the results of clinical trials with the platelet-derived growth factor, becaplermin, the tissue-engineered products Dermagraft and Apligraf, and Hyaff which is an ester of hyaluronic acid. In patients with an infected foot ulcer, encouraging results were obtained with the granulocyte-colony stimulating factor, Filgrastim.

Becaplermin↗

Corneal ulceration in Tanzanian children: relationship between measles and vitamin A deficiency.

Two 3-year prospective studies from 1982-1984 and 1986-1988 in Tanzania identified 189 children with corneal ulceration, of whom 31 (16.4%) were due to vitamin A deficiency. In 1982-1984, vitamin A deficiency was responsible for 23.4% of corneal ulcers (25 of 107) compared with 7.3% (6 of 82) from 1986-1988 (P = 0.006). It is postulated that the decrease in corneal ulceration due to vitamin A deficiency can be attributed to improved measles immunization coverage.

Child, Preschool↗

Corneal ulceration in Tanzanian children: relationship between malaria and herpes simplex keratitis.

Two 3-year prospective studies from 1982-1984 and 1986-1988 in Tanzania identified 189 children with corneal ulceration, of whom 92 (48.7%) were due to herpes simplex keratitis. In 1982-1984 herpes simplex keratitis was responsible for 35.5% of corneal ulcers (38 of 107), compared with 65.8% (54 of 82) in 1986-1988 (P = 0.00006). It is postulated that the increase in corneal ulceration due to herpes simplex keratitis can be attributed to an increase in the incidence and severity of malaria infection.

Age Factors↗

The effect of regular callus removal on foot pressures.

The optimum frequency of callus removal is unknown. This study shows that in-shoe dynamic plantar pressure measurement can quantify the effect of callus removal in relation with the frequency of podiatric treatment in diabetic ulcer patients. Three groups of diabetic neuropathic patients were studied. Group 0 consisted of six patients who presented for the first time ever for callus removal and who did not have a history of ulceration. The other two groups had a history of ulceration and required regular podiatry treatment: every 6-8 weeks for 10 patients in group A, and every 3-4 weeks for eight patients in group B. Peak plantar pressures were measured using the F-SCAN system, before and after removal of callus, which was weighed to further quantify the effect of podiatry. When callus was removed, peak pressures fell by 32.1 +/- 8.4% (p = .014) in group 0, by 30.9 +/- 4.5% (p < .005) in group A, and by 24.8 +/- 4.0% (p = .005) in group B. The mean weight of callus removed was not significantly different in the three groups. This suggests that the weight of callus is unlikely to be a reliable guide to assess the time intervals between podiatry appointments. However, the measurement of plantar pressures using a dynamic in-shoe plantar pressure device has proven to be a functional, objective, and quantifiable indicator in the assessment of podiatric treatment.

Adult↗

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Attitude of Health Personnel↗

Diabetic foot ulcers.

Nurses caring for people with diabetes can have an impact on the assessment and treatment of diabetic foot problems. This article describes a simple staging system to help in this important work.

Biomechanical Phenomena↗

An overview of foot disease in patients with diabetes.

Effective management of diabetic foot disease requires a multidisciplinary approach and good communication between all healthcare professionals involved. This article provides an overview of the main factors that need to be considered when assessing patients with diabetic foot disease.

Aged↗

Visual outcome with +10 diopter sphere correction after intracapsular cataract extraction.

BACKGROUND: The aim of curing cataract blindness is to restore the patient's vision after surgery. The aim of the study was to determine the proportion of surgeries done for cataract blind patients and the visual outcome with +10 diopter sphere (DS) aphakic correction in two consecutive years. METHODS: Of the cataract operations done in the years 1995 and 1996, 8-15 cases were selected from each month by proportionate simple random sampling. Thirty-two (32) were excluded for incomplete or missing records. One hundred and eighteen (118) and one hundred (100) patient records were analyzed for 1995 and 1996 respectively. RESULTS: The patients' ages ranged from 40 to 80 years and all had age related cataract. There were 161 males and 57 females. All had intracapsular cataract extraction (ICCE) without intraocular lens implantation. Eighty-nine patients (75%) and seventy-six patients (76%) had their sight restored in 1995 and 1996 respectively. The proportion of surgeries on blind patients' was 31% and 42% respectively. The proportion of those who remained blind after surgery was the same for both years (2%). Using chi-square test, there was a statistically significant difference in the patients' vision status after ICCE with +10 DS correction (1995, p = 0.021; 1996, p = 0.017) but no difference in the visual outcome due to gender. [1995, p = 2.09; 1996, p = 1.98 (Yates correction applied)] [corrected]. CONCLUSION: Intracapsular cataract extraction with +10 DS correction improves the patients vision status and priority must be given to those already blind.

Adult↗