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Biomedical subjects

A Fingerhut

Publications and source records attributed to A Fingerhut.

At least 127 records · Page 7Linked to original sources

Povidone-iodine enema as a preoperative bowel preparation for colorectal surgery. A bacteriologic study.

To evaluate the effects of povidone-iodine (PI) enema on the bacterial flora of colorectal mucosa, the authors studied 113 patients who were candidates for colorectal surgery. The study of the rectum included 72 patients. Total bacterial concentrations after a PI enema (N = 44) were significantly lower than after a simple water enema (N = 12, P less than 0.001), or than after a water enema associated with intravenous metronidazole (N = 16, P less than 0.01). The study of the colon included 41 patients. Total bacterial concentrations did not differ after a PI enema (N = 24) than after a water enema (N = 11); both groups were associated with intravenous metronidazole. In contrast, both preparations significantly reduced bacterial concentrations when compared with oral administration of polyethyleneglycol (N = 6, P less than 0.01). Similar results were observed in rectal and colonic studies, when analysis was restricted to the anaerobic flora. PI is an antiseptic that, when administered alone in an enema or in association with metronidazole, significantly reduces bacterial concentrations in the mucosa of the colon and rectum. It may be proposed as a simple preoperative preparation for colorectal surgery.

Bacteria, Aerobic↗

[Congenital mesoblastic nephroma in the adult].

Congenital mesoblastic nephroma is a benign neoplasm of the kidney which is usually diagnosed during the first three months of life. We report herein a case of mesoblastic nephroma in a 69 year-old man. At this age, diagnosis can only be made by histopathologic examination of the operative specimen. This was the case for our patient and the five other cases reported in the literature. Histogenesis of mesoblastic nephroma is open to debate: mesenchymal origin for some authors, tumor of the blastema for most of the others.

Aged↗

Closed peritoneal lavage in the diagnosis of non traumatic acute abdomen.

The records of 22 consecutive patients with a non-traumatic ill-defined acute abdomen having diagnostic closed peritoneal lavage, were reviewed retrospectively. All patients had one or more risk factors. Peritoneal lavage was performed under visual control and its diagnostic value was based on the comparison with the definitive diagnosis, based on laparatomy and complementary tests. There were 12 positive results with 11 true positives (7 cases of peritonitis, and 4 of visceral necrosis) and 1 false positive. There were 10 negative results with 9 true negatives and 1 false negative. Sensitivity of peritoneal lavage was 0.91%, specificity 0.90%, positive predictivity 0.91% and negativity 0.90%. Overall mortality was 45%. The limits of the procedure appear to be the infections or localized abscesses. Peritoneal lavage as a simple and easy method, is suitable for high-risk patients when the choice is between immediate operation with possible side-effects or delay with possible adverse course of the abdominal lesion, and permits immediate indication for surgery in case of positivity.

Abdomen, Acute↗

Ventral incisional hernias: incidence, date of recurrence, localization and risk factors.

Over an 8-year period, 1246 consecutive patients undergoing abdominal surgery were followed up postoperatively for a maximum of 5 years to study retrospectively the incidence, date of occurrence location and risk factors of incisional hernia. Only 1081 cases were assessable. Overall 94 incisional hernias (9%) were evidenced. The actuarial rate of incisional hernia was shown to be 13% at 5 years, occurring during the first 24 months in 80% of cases. Risk factors were analyzed according to four parameters: patient's status, underlying disease, surgical technique, postoperative complications. Morbid obesity, underlying disease, emergency surgery, wound or deep abscesses or early reoperation were all statistically significant factors. From the overall analysis of results it is shown that at 5 years 13% of patients at risk present postoperative incisional hernia. The two main factors on which surgeons are able to act preventively are the choice of incision site and the onset of wound abscesses. Subcostal incision is the most suitable and prevention of abscesses can be obtained essentially by antibiotic prophylaxis.

Female↗

A new sphincter-splitting operation for surgical access to low-lying tumors of the rectum.

Fifty-eight patients underwent anterior anorectotomy for removal of intrarectal tumor. The mean age of patients was 69 years: 33 were over 70.26 tumors were benign and 32 malignant. There were no postoperative deaths during hospital stay or the 30 days following discharge. Six abscesses and 2 self-limiting urethral fistulas were diagnosed in 2 male patients. The wound healed at day 14 on the average. Sphincter function was judged to be poor or average in 2 cases each and normal in the remaining 54. One patient had local recurrence at 6 years, amenable to reoperation. Five patients died of their cancer between 10 months and 2 years. Anterior anorectotomy permits exposition up to 14 cm from the anal verge, is not mutilating, can be performed under spinal anesthesia, and is recommended for removal of benign rectal tumors as well as small carcinomas in patients physically or mentally unfit for major abdominal surgery.

Adult↗

[Therapeutic attitude in choledocoduodenal fistulas complicating duodenal ulcer].

The authors present 5 observations of choledocoduodenal fistula complicating chronic duodenal ulcer disease. Four cases were observed in Central Africa, the other in France. After a study of the frequency, and especially of the higher incidence in Africa, the authors review the problems associated with the pathology, clinical and diagnostic aspects of this complication. Moreover, they evoke the essential problems of management, as based on their experience and a review of the literature: medical vs. surgical treatment, should and how they treat the biliary lesions. Their individual results are criticized. A policy for the management of this complication is considered.

Adult↗

[Eosinophilic granuloma of the small intestine, colon and rectum].

The authors reviewed the literature on predominantly eosinophilic inflammatory infiltrations of the bowel wall. Epidemiologic, pathologic and etiologic aspects are first presented, followed by specific clinical problems, radiology, endoscopy and treatment of this unusual illness.

Biopsy↗

[Gastric eosinophilic granuloma : value of endoscopic polypectomy. Apropos of 2 cases].

Two ulcerated, sessile, gastric eosinophilic granulomas, measuring 5 and 10 mm in diameter, were diagnosed by endoscopic polypectomy (accurate prior forceps biopsy had not established accurate diagnosis). The patients, aged 76 and 74 years, had anemia and epigastric pain respectively. None of the usual etiologies (parasitic, chemical, traumatic and ulcerous) were found. Survival, clinical symptoms and location were similar to data reported in the literature, which are briefly reviewed. The value of endoscopic polypectomy is emphasized. With this procedure, pedunculated forms can be treated and sessile forms diagnosed, thus avoiding a useless gastrectomy and its hazards in these elderly patients.

Aged↗